Doxorubicin

signal transducer and activator of transcription 3 ; Mus musculus







23 Article(s)
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1 34933182 LCN2 deficiency ameliorates doxorubicin-induced cardiomyopathy in mice. 2022 Jan 15 2
2 35584053 Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance. 2022 Jun 13 2
3 34600949 Targeted elimination of myeloid-derived suppressor cells via regulation of the STAT pathway alleviates tumor immunosuppression in neuroblastoma. 2021 Dec 2
4 31866378 Atorvastatin protects cardiomyocyte from doxorubicin toxicity by modulating survivin expression through FOXO1 inhibition. 2020 Jan 4
5 31942696 STAT3 inhibitory stattic enhances immunogenic cell death induced by chemotherapy in cancer cells. 2020 Jun 1
6 31958751 MiR-526b-3p mediates doxorubicin-induced cardiotoxicity by targeting STAT3 to inactivate VEGFA. 2020 Mar 3
7 32653978 Formulation of Stattic as STAT3 inhibitor in nanostructured lipid carriers (NLCs) enhances efficacy of doxorubicin in melanoma cancer cells. 2020 Dec 3
8 30472367 Activation of cardiac TrkB receptor by its small molecular agonist 7,8-dihydroxyflavone inhibits doxorubicin-induced cardiotoxicity via enhancing mitochondrial oxidative phosphorylation. 2019 Jan 1
9 30675314 Metformin selectively targets 4T1 tumorspheres and enhances the antitumor effects of doxorubicin by downregulating the AKT and STAT3 signaling pathways. 2019 Feb 6
10 29753615 Targeting the proinflammatory cytokines, oxidative stress, apoptosis and TGF-β1/STAT-3 signaling by irbesartan to ameliorate doxorubicin-induced hepatotoxicity. 2018 Aug 2
11 29078883 Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer. 2017 Nov 1
12 26526549 JAK2/STAT3 Pathway Mediates Protection of Metallothionein Against Doxorubicin-Induced Cytotoxicity in Mouse Cardiomyocytes. 2016 May 8
13 26980746 Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors. 2016 Apr 12 1
14 27323684 Protection against doxorubicin-induced myocardial dysfunction in mice by cardiac-specific expression of carboxyl terminus of hsp70-interacting protein. 2016 Jun 21 1
15 27340780 Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3. 2016 Jul 26 1
16 25660617 Protective effects of endothelin receptor A and B inhibitors against doxorubicin-induced cardiomyopathy. 2015 Mar 15 1
17 26255115 Downregulation of STAT3 phosphorylation enhances tumoricidal effect of IL-15-activated dendritic cell against doxorubicin-resistant lymphoma and leukemia via TNF-α. 2015 Oct 4
18 26536361 FL3, a Synthetic Flavagline and Ligand of Prohibitins, Protects Cardiomyocytes via STAT3 from Doxorubicin Toxicity. 2015 3
19 24812279 P53 inhibition exacerbates late-stage anthracycline cardiotoxicity. 2014 Jul 1 3
20 21738612 Overexpression of Nrdp1 in the heart exacerbates doxorubicin-induced cardiac dysfunction in mice. 2011 1
21 14566054 Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age. 2003 Oct 28 1
22 11524388 Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase. 2001 Aug 28 2
23 10618415 Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy. 2000 Jan 4 3