Dipeptides

RAN, member RAS oncogene family ; Homo sapiens







26 Article(s)
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Title
Pub. Year
#Total Relationships
1 33431483 Inducible expression of human C9ORF72 36x G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice. 2021 Jan 11 1
2 33619157 Concomitant gain and loss of function pathomechanisms in C9ORF72 amyotrophic lateral sclerosis. 2021 Apr 1
3 34450161 The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene. 2021 Oct 1
4 32100453 C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis. 2020 Apr 2
5 32375063 Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36. 2020 Jul 22 1
6 32639008 Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD. 2020 Dec 11 1
7 32702342 It Takes Two to Tango: DPRs in ALS and SCA36. 2020 Jul 22 1
8 30503283 The Hairpin Form of r(G4C2)exp in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules. 2019 Feb 21 1
9 30617154 Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress. 2019 Feb 2
10 30639592 Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins. 2019 Apr 15 1
11 31148094 Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis. 2019 Oct 1
12 31358992 RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats. 2019 Sep 1
13 29323119 CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts. 2018 Jan 11 1
14 30213863 Repeat-associated non-ATG (RAN) translation. 2018 Oct 19 1
15 30322030 The Emerging Role of DNA Damage in the Pathogenesis of the C9orf72 Repeat Expansion in Amyotrophic Lateral Sclerosis. 2018 Oct 12 1
16 28744202 RNA Misprocessing in C9orf72-Linked Neurodegeneration. 2017 1
17 28973350 C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity. 2017 Dec 15 1
18 27776165 Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity. 2016 2
19 25575510 Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity. 2015 May 1 2
20 26308899 GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport. 2015 Sep 3 1
21 26374446 Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers. 2015 Dec 1
22 26637796 C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD. 2015 Dec 2 1
23 24371143 TMPyP4 porphyrin distorts RNA G-quadruplex structures of the disease-associated r(GGGGCC)n repeat of the C9orf72 gene and blocks interaction of RNA-binding proteins. 2014 Feb 21 1
24 25005000 Repeat-associated non-AUG translation and its impact in neurodegenerative disease. 2014 Oct 1
25 25521377 Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death. 2014 Dec 17 1
26 23423380 The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures. 2013 Apr 5 1