Ceramides

caspase 3 ; Homo sapiens







73 Article(s)
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1 32707889 Molecular and Functional Analysis of Choline Transporters and Antitumor Effects of Choline Transporter-Like Protein 1 Inhibitors in Human Pancreatic Cancer Cells. 2020 Jul 22 1
2 28858294 The ceramide pathway is involved in the survival, apoptosis and exosome functions of human multiple myeloma cells in vitro. 2018 Apr 1
3 27055903 Sphingolipids Contribute to Human Atherosclerotic Plaque Inflammation. 2016 Jun 1
4 27852416 [Effects and mechanism ofitraconazole on prostate cancer PC-3 cell apoptosis]. 2016 Oct 25 1
5 26090071 Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation. 2015 1
6 26280656 LAPTM4B facilitates late endosomal ceramide export to control cell death pathways. 2015 Oct 1
7 24079644 Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress. 2014 Mar 1
8 25240837 Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation. 2014 Dec 1
9 23495037 Mechanisms of ceramide-induced COX-2-dependent apoptosis in human ovarian cancer OVCAR-3 cells partially overlapped with resveratrol. 2013 Aug 1
10 24044897 Cytosolic phospholipase A2α upregulation mediates apoptotic neuronal death induced by aggregated amyloid-β peptide1-42. 2013 Nov 1
11 22306364 Ordering of ceramide formation and caspase-9 activation in CD95L-induced Jurkat leukemia T cell apoptosis. 2012 Apr 2
12 21157428 Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes. 2011 Jan 19 1
13 21259059 Ceramide induces apoptosis via caspase-dependent and caspase-independent pathways in mesenchymal stem cells derived from human adipose tissue. 2011 Sep 2
14 21271550 [HIV-1 neuropathogenesis: therapeutic strategies against neuronal loss induced by gp120/Tat glycoprotein in the central nervous system]. 2011 Jan 16 1
15 21333695 Role of JNK/ATF-2 pathway in inhibition of thrombospondin-1 (TSP-1) expression and apoptosis mediated by doxorubicin and camptothecin in FTC-133 cells. 2011 May 1
16 19027085 De novo ceramide synthesis is responsible for the anti-tumor properties of camptothecin and doxorubicin in follicular thyroid carcinoma. 2009 May 1
17 18054155 Ceramide induces p38 MAPK-dependent apoptosis and Bax translocation via inhibition of Akt in HL-60 cells. 2008 Feb 18 1
18 18176793 Ceramide induces release of mitochondrial proapoptotic proteins in caspase-dependent and -independent manner in HT-29 cells. 2008 Jan 1
19 18623086 Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway. 2008 Sep 15 2
20 17239851 Nitric oxide-enhanced caspase-3 and acidic sphingomyelinase interaction: a novel mechanism by which airway epithelial cells escape ceramide-induced apoptosis. 2007 Feb 15 2
21 17240190 Palmitate and oleate have distinct effects on the inflammatory phenotype of human endothelial cells. 2007 Feb 1
22 16359673 Involvement of de novo ceramide biosynthesis in macrophage death induced by activation of ATP-sensitive P2X7 receptor. 2006 Jan 9 1
23 16545138 CD40L induces multidrug resistance to apoptosis in breast carcinoma and lymphoma cells through caspase independent and dependent pathways. 2006 Mar 18 1
24 16549336 Acid sphingomyelinase mediated release of ceramide is essential to trigger the mitochondrial pathway of apoptosis by galectin-1. 2006 Nov 1
25 16971166 Thrombospondin-1 C-terminal-derived peptide protects thyroid cells from ceramide-induced apoptosis through the adenylyl cyclase pathway. 2006 1
26 15905098 Ceramide induces neuronal apoptosis through mitogen-activated protein kinases and causes release of multiple mitochondrial proteins. 2005 Jul 1
27 16170023 Resistance to TRAIL is associated with defects in ceramide signaling that can be overcome by exogenous C6-ceramide without requiring down-regulation of cellular FLICE inhibitory protein. 2005 Sep 1
28 14871831 Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis. 2004 Feb 1 3
29 15203188 Ceramide-induced apoptosis: role of catalase and hepatocyte growth factor. 2004 Jul 15 2
30 15273737 Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB. 2004 Sep 2 1
31 15361788 Acid sphingomyelinase in macrophage apoptosis. 2004 Oct 1
32 15466700 Sphingosine-dependent apoptosis: a unified concept based on multiple mechanisms operating in concert. 2004 Oct 12 1
33 15569266 Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells. 2004 Dec 1
34 12492473 Signaling events mediating activation of brain ethanolamine plasmalogen hydrolysis by ceramide. 2003 Jan 2
35 12511568 Ceramide increases oxidative damage due to inhibition of catalase by caspase-3-dependent proteolysis in HL-60 cell apoptosis. 2003 Mar 14 4
36 12576296 Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells. 2003 Jun 3
37 12588799 Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. 2003 Mar 1 1
38 12691738 Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway. 2003 Mar 1
39 12832039 Annexin A1 processing is associated with caspase-dependent apoptosis in BZR cells. 2003 Jul 10 1
40 12904547 Bacterial ceramides and sphingophospholipids induce apoptosis of human leukaemic cells. 2003 Aug 3
41 12975495 Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells. 2003 Nov 1
42 14674699 Commitment to apoptosis by ceramides depends on mitochondrial respiratory function, cytochrome c release and caspase-3 activation in Hep-G2 cells. 2003 Dec 1
43 11792463 Serum deprivation increases ceramide levels and induces apoptosis in undifferentiated HN9.10e cells. 2002 Apr 1
44 11894136 Ceramide involvement in homocamptothecin- and camptothecin-induced cytotoxicity and apoptosis in colon HT29 cells. 2002 Apr 1
45 11960374 P53 mediates ceramide-induced apoptosis in SKN-SH cells. 2002 Mar 27 1
46 12032677 Control of ceramide-induced apoptosis by IGF-1: involvement of PI-3 kinase, caspase-3 and catalase. 2002 Jun 5
47 12037683 Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells. 2002 Jun 6 2
48 12069099 Ceramide-dependent caspase 3 activation is prevented by coenzyme Q from plasma membrane in serum-deprived cells. 2002 Apr 2
49 12207171 Mitochondrial cytochrome c release precedes transmembrane depolarisation and caspase-3 activation during ceramide-induced apoptosis of Jurkat T cells. 2002 Oct 2
50 12213802 Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B. 2002 Nov 8 2