gemcitabine

caspase 3 ; Homo sapiens







47 Article(s)
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1 35406478 Gemcitabine Cooperates with Everolimus to Inhibit the Growth of and Sensitize Malignant Meningioma Cells to Apoptosis Induced by Navitoclax, an Inhibitor of Anti-Apoptotic BCL-2 Family Proteins. 2022 Mar 27 1
2 34048785 In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells. 2021 Aug 15 1
3 34624736 Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer. 2021 Nov 19 1
4 34805140 Effect of Photodynamic Therapy on Gemcitabine-Resistant Cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR. 2021 1
5 34955688 Modulated Electro-Hyperthermia Supports the Effect of Gemcitabine Both in Sensitive and Resistant Pancreas Adenocarcinoma Cell Lines. 2021 1
6 32277442 A comparative molecular analysis of DNA damage response, cell cycle progression, viability and apoptosis of malignant granulosa cells exposed to gemcitabine and cisplatin. 2020 May 1
7 30320607 Co-operation of ABT-199 and gemcitabine in impeding DNA damage repair and inducing cell apoptosis for synergistic therapy of T-cell acute lymphoblastic leukemia. 2019 Feb 1
8 30992462 p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma. 2019 Apr 16 1
9 30308458 Melatonin and its metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (afmk) enhance chemosensitivity to gemcitabine in pancreatic carcinoma cells (PANC-1). 2018 Dec 1
10 30454541 [Microwave Hyperthermia Combined with Gemcitabine Inhibits Proliferation 
and Induces Apoptosis of Human Lung Squamous Carcinoma Cells]. 2018 Nov 20 2
11 30589026 Combined effect of 125I and gemcitabine on PANC-1 cells: Cellular apoptosis and cell cycle arrest. 2018 1
12 28055291 Metuzumab enhanced chemosensitivity and apoptosis in non-small cell lung carcinoma. 2017 Jan 2 1
13 28766646 A cascade enzymatic reaction activatable gemcitabine prodrug with an AIE-based intracellular light-up apoptotic probe for in situ self-therapeutic monitoring. 2017 Aug 25 1
14 29048622 Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells. 2017 Nov 1
15 29118324 Suppression of the FA pathway combined with CHK1 inhibitor hypersensitize lung cancer cells to gemcitabine. 2017 Nov 8 1
16 27779693 Metformin potentiates the anticancer activities of gemcitabine and cisplatin against cholangiocarcinoma cells in vitro and in vivo. 2016 Dec 2
17 27833761 E1A enhances cellular sensitivity to DNA-damage-induced apoptosis through PIDD-dependent caspase-2 activation. 2016 1
18 25344906 Thymoquinone Pretreatment Overcomes the Insensitivity and Potentiates the Antitumor Effect of Gemcitabine Through Abrogation of Notch1, PI3K/Akt/mTOR Regulated Signaling Pathways in Pancreatic Cancer. 2015 Apr 1
19 25348515 Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. 2015 Jan 1 1
20 26050647 Quercetin Enhances Chemosensitivity to Gemcitabine in Lung Cancer Cells by Inhibiting Heat Shock Protein 70 Expression. 2015 Nov 1
21 26112218 Pyruvate kinase isoenzyme M2 is a therapeutic target of gemcitabine-resistant pancreatic cancer cells. 2015 Aug 1 1
22 26156229 The combination of intravenous Reolysin and gemcitabine induces reovirus replication and endoplasmic reticular stress in a patient with KRAS-activated pancreatic cancer. 2015 Jul 10 1
23 23995783 Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase. 2014 Jul 17 1
24 24128051 Gemcitabine sensitizes lung cancer cells to Fas/FasL system-mediated killing. 2014 Feb 3
25 25240403 Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-κB signaling. 2014 Sep 20 1
26 21889367 Small interfering RNA targeting heat shock protein 70 enhances chemosensitivity in human bladder cancer cells. 2013 Aug 1
27 22488590 Inhibition of constitutively activated phosphoinositide 3-kinase/AKT pathway enhances antitumor activity of chemotherapeutic agents in breast cancer susceptibility gene 1-defective breast cancer cells. 2013 Sep 1
28 23833637 SmacN7 enhances the sensitivity of pancreatic cancer cells to tumor necrosis factor-related apoptosis-inducing ligand or gemcitabine. 2013 Jun 1
29 24312717 Expression of heat shock protein 70 modulates the chemoresponsiveness of pancreatic cancer. 2013 Nov 2
30 24649271 Efficacy of gemcitabine and cetuximab combination treatment in head and neck squamous cell carcinoma. 2013 Sep 1
31 23047891 BMS-754807, a small-molecule inhibitor of insulin-like growth factor-1 receptor/insulin receptor, enhances gemcitabine response in pancreatic cancer. 2012 Dec 1
32 21305255 Enhanced effect of gemcitabine by emodin against pancreatic cancer in vivo via cytochrome C-regulated apoptosis. 2011 May 1
33 20299819 Gemcitabine induces the VMP1-mediated autophagy pathway to promote apoptotic death in human pancreatic cancer cells. 2010 1
34 20302733 [An experimental study of gemcitabine inducing pancreatic cancer cell apoptosis potentiated by nuclear factor-kappa B P65 siRNA]. 2010 Jan 15 1
35 19223497 Oncolytic adenoviral mutants with E1B19K gene deletions enhance gemcitabine-induced apoptosis in pancreatic carcinoma cells and anti-tumor efficacy in vivo. 2009 Mar 1 1
36 19437237 Effect of hyperthermia combined with gemcitabine on apoptotic cell death in cultured human pancreatic cancer cell lines. 2009 May 1
37 18430374 Synergy of gemcitabine and lidamycin associated with NF-kappaB downregulation in pancreatic carcinoma cells. 2008 May 1
38 17159604 Gemcitabine-induced apoptosis in 5637 cell line: an in-vitro model for high-risk superficial bladder cancer. 2007 Feb 1
39 18333132 Gene expression analysis for predicting gemcitabine sensitivity in pancreatic cancer patients. 2007 1
40 16397047 p8 is a new target of gemcitabine in pancreatic cancer cells. 2006 Jan 1 4
41 16467107 The schedule-dependent effects of the novel antifolate pralatrexate and gemcitabine are superior to methotrexate and cytarabine in models of human non-Hodgkin's lymphoma. 2006 Feb 1 1
42 16505115 c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-beta-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells. 2006 Feb 1
43 15726400 Apoptosis by gemcitabine in non-small cell lung cancer cell line KNS62 is induced downstream of caspase 8 and is profoundly blocked by Bcl-xL over-expression. 2005 Jun 1
44 15867245 RNA interference demonstrates a novel role for integrin-linked kinase as a determinant of pancreatic adenocarcinoma cell gemcitabine chemoresistance. 2005 May 1 1
45 16425399 MSX2 overexpression inhibits gemcitabine-induced caspase-3 activity in pancreatic cancer cells. 2005 Nov 21 3
46 15585396 Caspase-3 drives apoptosis in pancreatic cancer cells after treatment with gemcitabine. 2004 Dec 1
47 12479703 Caspase activation is required for gemcitabine activity in multiple myeloma cell lines. 2002 Nov 1