ursolic acid

caspase 3 ; Homo sapiens







53 Article(s)
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1 33028983 Ursolic acid reduces hepatocellular apoptosis and alleviates alcohol-induced liver injury via irreversible inhibition of CASP3 in vivo. 2021 Jul 1
2 33278391 Inhibition of breast cancer stem-like cells by a triterpenoid, ursolic acid, via activation of Wnt antagonist, sFRP4 and suppression of miRNA-499a-5p. 2021 Jan 15 1
3 31527378 Suppressive Effects of Ursolic Acid on Human Endometriotic Stromal Cells Survival. 2020 1
4 32539919 Ursolic acid potentiated oxaliplatin to induce apoptosis in colorectal cancer RKO cells. 2020 Jun 1 2
5 32545262 Differential Anti-Proliferative and Anti-Migratory Activities of Ursolic Acid, 3-O-Acetylursolic Acid and Their Combination Treatments with Quercetin on Melanoma Cells. 2020 Jun 11 1
6 32617130 Inhibitory Effect of Ursolic Acid on Ultraviolet B Radiation-Induced Oxidative Stress and Proinflammatory Response-Mediated Senescence in Human Skin Dermal Fibroblasts. 2020 1
7 30772887 Ursolic Acid Exhibits Potent Anticancer Effects in Human Metastatic Melanoma Cancer Cells (SK-MEL-24) via Apoptosis Induction, Inhibition of Cell Migration and Invasion, Cell Cycle Arrest, and Inhibition of Mitogen-Activated Protein Kinase (MAPK)/ERK Signaling Pathway. 2019 Feb 17 1
8 31061311 Ursolic Acid Inhibits Tumor Growth via Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells. 2019 1
9 31545303 Inhibition of Proliferation of SGC7901 and BGC823 Human Gastric Cancer Cells by Ursolic Acid Occurs Through a Caspase-Dependent Apoptotic Pathway. 2019 Sep 12 1
10 29435058 Ursolic acid activates the apoptosis of prostate cancer via ROCK/PTEN mediated mitochondrial translocation of cofilin-1. 2018 Mar 1
11 29956797 Ursolic acid elicits intrinsic apoptotic machinery by downregulating the phosphorylation of AKT/BAD signaling in human cisplatin‑resistant oral cancer CAR cells. 2018 Sep 1
12 30597956 Ursolic Acid Induces Apoptosis in Colorectal Cancer Cells Partially via Upregulation of MicroRNA-4500 and Inhibition of JAK2/STAT3 Phosphorylation. 2018 Dec 29 1
13 28801966 Ursolic Acid, a Natural Nutraceutical Agent, Targets Caspase3 and Alleviates Inflammation-Associated Downstream Signal Transduction. 2017 Dec 1
14 29042957 Ursolic acid inhibits breast cancer growth by inhibiting proliferation, inducing autophagy and apoptosis, and suppressing inflammatory responses via the PI3K/AKT and NF-κB signaling pathways in vitro. 2017 Oct 1
15 29228621 Synergism of ursolic acid and cisplatin promotes apoptosis and enhances growth inhibition of cervical cancer cells via suppressing NF-κB p65. 2017 Nov 14 1
16 29798594 [Effect of ursolic acid on proliferation and apoptosis of human osteosarcoma cell line U2-OS]. 2017 Nov 15 3
17 27104510 The Apoptotic Effect of Ursolic Acid on SK-Hep-1 Cells is Regulated by the PI3K/Akt, p38 and JNK MAPK Signaling Pathways. 2016 Apr 20 2
18 27171502 Ursolic Acid Triggers Apoptosis in Human Osteosarcoma Cells via Caspase Activation and the ERK1/2 MAPK Pathway. 2016 Jun 1 1
19 27698874 Anti-cancer effect of ursolic acid activates apoptosis through ROCK/PTEN mediated mitochondrial translocation of cofilin-1 in prostate cancer. 2016 Oct 1
20 25230943 Ursolic acid induced apoptotic cell death following activation of caspases in isolated human melanoma cells. 2015 Feb 1
21 25621065 Ursolic acid inhibits the invasive phenotype of SNU-484 human gastric cancer cells. 2015 Feb 1
22 25778894 [Effect of ursolic acid on proliferation of T lymphoma cell lines Hut-78 cells and its mechanism]. 2015 Feb 1
23 26503559 Ursolic Acid Induces Apoptosis of Prostate Cancer Cells via the PI3K/Akt/mTOR Pathway. 2015 1
24 25383044 Ursolic acid induces cell cycle arrest and apoptosis of gallbladder carcinoma cells. 2014 1
25 25520072 Ursolic acid promotes apoptosis of SGC-7901 gastric cancer cells through ROCK/PTEN mediated mitochondrial translocation of cofilin-1. 2014 1
26 26629938 Ursolic Acid Inhibits the Proliferation of Gastric Cancer Cells by Targeting miR-133a. 2014 1
27 23000344 Ursolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cells. 2013 Jan 1
28 23194884 Delivery of ursolic acid (UA) in polymeric nanoparticles effectively promotes the apoptosis of gastric cancer cells through enhanced inhibition of cyclooxygenase 2 (COX-2). 2013 Jan 30 4
29 23325562 Activation of AMP-activated protein kinase and phosphorylation of glycogen synthase kinase3 β mediate ursolic acid induced apoptosis in HepG2 liver cancer cells. 2013 Nov 2
30 23737956 Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells. 2013 1
31 24071474 Ursolic acid induces apoptosis of SW480 cells via p53 activation. 2013 Dec 1
32 24122993 Ursolic acid inhibits the growth of colon cancer-initiating cells by targeting STAT3. 2013 Oct 1
33 24399733 Inhibition of Wnt/β-catenin signaling mediates ursolic acid-induced apoptosis in PC-3 prostate cancer cells. 2013 1
34 22353043 Ursolic acid inhibits proliferation and induces apoptosis in human glioblastoma cell lines U251 by suppressing TGF-β1/miR-21/PDCD4 pathway. 2012 Aug 1
35 22791147 Ursolic acid from Oldenlandia diffusa induces apoptosis via activation of caspases and phosphorylation of glycogen synthase kinase 3 beta in SK-OV-3 ovarian cancer cells. 2012 3
36 21716649 Ursolic acid inhibits proliferation and induces apoptosis of cancer cells in vitro and in vivo. 2011 2
37 20005942 Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines. 2010 Apr 1
38 20137120 [Apoptosis of jurkat cells induced by ursolic acid and its mechanism]. 2010 Feb 1
39 20415421 Oleanolic acid and ursolic acid induce apoptosis in HuH7 human hepatocellular carcinoma cells through a mitochondrial-dependent pathway and downregulation of XIAP. 2010 May 26 1
40 20943386 Apoptotic action of ursolic acid isolated from Corni fructus in RC-58T/h/SA#4 primary human prostate cancer cells. 2010 Nov 15 1
41 19174695 Downregulation of survivin and activation of caspase-3 through the PI3K/Akt pathway in ursolic acid-induced HepG2 cell apoptosis. 2009 Apr 7
42 19545597 Phosphorylation of Bcl-2 and activation of caspase-3 via the c-Jun N-terminal kinase pathway in ursolic acid-induced DU145 cells apoptosis. 2009 Sep 2
43 18097588 Differential involvement of mitochondria during ursolic acid-induced apoptotic process in HaCaT and M4Beu cells. 2008 Jan 1
44 17352226 Up-regulation of matrix metalloproteinase family gene involvement in ursolic acid-induced human lung non-small carcinoma cell apoptosis. 2007 Jan-Feb 1
45 16570804 [Effect of ursolic acid on caspase-3 and PARP expression of human MCF-7 cells]. 2006 Jan 4
46 17177841 Antiproliferative and antiviral mechanisms of ursolic acid and dexamethasone in cervical carcinoma cell lines. 2006 Nov-Dec 1
47 15523687 Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells. 2005 Mar 10 2
48 15583801 Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells. 2005 Jan 5
49 16012738 Molecular mechanism of ursolic acid induced apoptosis in poorly differentiated endometrial cancer HEC108 cells. 2005 Aug 4
50 12792782 Ursolic acid induces apoptosis through caspase-3 activation and cell cycle arrest in HaCat cells. 2003 Jul 2