Genistein

caspase 3 ; Homo sapiens







49 Article(s)
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1 33347704 Genistein enhances the effects of L-asparaginase on inducing cell apoptosis in human leukemia cancer HL-60 cells. 2021 May 1
2 34663173 Genistein alleviates H2O2-induced senescence of human umbilical vein endothelial cells via regulating the TXNIP/NLRP3 axis. 2021 Dec 1
3 31579960 Genistein protects ovarian granulosa cells from oxidative stress via cAMP-PKA signaling. 2020 Feb 1
4 31912375 Evaluation of phytoestrogens in inducing cell death mediated by decreasing Annexin A1 in Annexin A1-knockdown leukemia cells. 2020 Jun 1
5 31985311 Beneficial effects of genistein in suppression of proliferation, inhibition of metastasis, and induction of apoptosis in PC3 prostate cancer cells. 2020 Jan 27 4
6 33164393 [Molecular mechanism of Puerariae Lobatae Radix in treatment of hepatocellular carcinoma based on network pharmacology]. 2020 Sep 1
7 31438633 Induction of G2/M Cell Cycle Arrest and Apoptosis by Genistein in Human Bladder Cancer T24 Cells through Inhibition of the ROS-Dependent PI3k/Akt Signal Transduction Pathway. 2019 Aug 21 1
8 31538075 Effects of genistein on anti-tumor activity of cisplatin in human cervical cancer cell lines. 2019 Sep 1
9 29202800 Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-κB/slug/E-cadherin pathway. 2017 Dec 4 1
10 26718793 Genistein inhibits the proliferation of human multiple myeloma cells through suppression of nuclear factor-κB and upregulation of microRNA-29b. 2016 Feb 1
11 27602162 Genistein inhibits A549 human lung cancer cell proliferation via miR-27a and MET signaling. 2016 Sep 1
12 27942504 Genistein Induces Apoptosis and Inhibits Proliferation of HT29 Colon Cancer Cells. 2016 Summer 2
13 26352862 Genistein enhances TRAIL-induced cancer cell death via inactivation of autophagic flux. 2015 Nov 1
14 24299158 Phytoestrogens induce apoptosis through a mitochondria/caspase pathway in human breast cancer cells. 2014 Aug 1
15 22716961 Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury. 2013 Jan 28 1
16 23356442 Induction of apoptosis in HeLa cells via caspase activation by resveratrol and genistein. 2013 Feb 1
17 23363563 Genistein ameliorates adverse cardiac effects induced by arsenic trioxide through preventing cardiomyocytes apoptosis. 2013 1
18 23909732 Novel genistein derivatives induce cell death and cell cycle arrest through different mechanisms. 2013 1
19 22452992 Anticancer activities of genistein-topotecan combination in prostate cancer cells. 2012 Nov 3
20 22626855 Genistein enhances the effect of trichostatin A on inhibition of A549 cell growth by increasing expression of TNF receptor-1. 2012 Aug 1 1
21 22931613 [Effect of livin gene suppression by genistein on apoptosis, cell cycle and proliferation of malignant melanoma LiBr cells]. 2012 Aug 2
22 19639378 Genistein and beta-carotene enhance the growth-inhibitory effect of trichostatin A in A549 cells. 2010 Feb 3
23 19959636 Inhibition of apoptosis in human retinal pigment epithelial cells treated with benzo(e)pyrene, a toxic component of cigarette smoke. 2010 May 1
24 19994890 Anticancer effects of flavonoid derivatives isolated from Millettia reticulata Benth in SK-Hep-1 human hepatocellular carcinoma cells. 2010 Jan 27 1
25 20138837 Lipid raft cholesterol and genistein inhibit the cell viability of prostate cancer cells via the partial contribution of EGFR-Akt/p70S6k pathway and down-regulation of androgen receptor. 2010 Mar 5 1
26 20944417 Genistein induced apoptotic cell death in adult T-cell leukemia cells through estrogen receptors. 2010 1
27 19082897 Isoflavone genistein protects human vascular endothelial cells against tumor necrosis factor-alpha-induced apoptosis through the p38beta mitogen-activated protein kinase. 2009 Jan 1
28 19091461 Combined effects of terazosin and genistein on a metastatic, hormone-independent human prostate cancer cell line. 2009 Apr 8 1
29 19723056 Involvement of both extrinsic and intrinsic apoptotic pathways in apoptosis induced by genistein in human cervical cancer cells. 2009 Aug 3
30 18092837 Chemoprotective action of resveratrol and genistein from apoptosis induced in human peripheral blood lymphocytes. 2008 Feb 1
31 18388472 Sensitization of the apoptotic effect of gamma-irradiation in genistein-pretreated CaSki cervical cancer cells. 2008 Mar 1
32 18761399 Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway. 2008 Oct 2
33 17490757 Caspase-3 status is a determinant of the differential responses to genistein between MDA-MB-231 and MCF-7 breast cancer cells. 2007 Jun 4
34 17689858 Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3. 2007 Nov 8 2
35 17699721 Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein. 2007 Aug 1
36 17725991 Stimulatory and inhibitory effects of genistein on human uterine leiomyoma cell proliferation are influenced by the concentration. 2007 Oct 1
37 16758967 [Effects of ERK5 MAPK signaling transduction pathway on the inhibition of genistein to breast cancer cells]. 2006 Mar 1
38 17132221 Apigenin suppresses cancer cell growth through ERbeta. 2006 Nov 1
39 15883821 Genistein-induced apoptosis via Akt signaling pathway in anaplastic large-cell lymphoma. 2005 Sep 1
40 15161029 Inhibitory effect of genistein and daidzein on ovarian cancer cell growth. 2004 Mar-Apr 1
41 15173388 Genistein at a concentration present in soy infant formula inhibits Caco-2BBe cell proliferation by causing G2/M cell cycle arrest. 2004 Jun 1
42 15315711 Potential mechanism of phytochemical-induced apoptosis in human prostate adenocarcinoma cells: Therapeutic synergy in genistein and beta-lapachone combination treatment. 2004 Aug 17 6
43 12657953 Prevention of metastatic pancreatic cancer growth in vivo by induction of apoptosis with genistein, a naturally occurring isoflavonoid. 2003 Apr 1
44 12793003 [Study on mechanisms of human gastric carcinoma cells apoptosis induced by genistein]. 2003 Mar 1
45 12441188 17beta-Estradiol and the phytoestrogen genistein attenuate neuronal apoptosis induced by the endoplasmic reticulum calcium-ATPase inhibitor thapsigargin. 2002 Dec 1
46 11741499 Protein tyrosine kinase inhibitors modulate radiosensitivity and radiation-induced apoptosis in K562 cells. 2001 Dec 1
47 10797567 Inhibition of UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermal carcinoma A431 cells by genistein. 2000 Apr 1
48 11374438 The mediating role of caspase-3 protease in the intracellular mechanism of genistein-induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP. 2000 Dec 1
49 10340389 Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein. 1999 May 20 1