15-deoxy-delta(12,14)-prostaglandin J2

peroxisome proliferator activated receptor gamma ; Mus musculus







45 Article(s)
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1 34175325 Intranasal 15d-PGJ2 ameliorates brain glucose hypometabolism via PPARγ-dependent activation of PGC-1α/GLUT4 signalling in APP/PS1 transgenic mice. 2021 Sep 15 6
2 31658492 Rosiglitazone alleviates intrahepatic cholestasis induced by α-naphthylisothiocyanate in mice: The role of circulating 15-deoxy-Δ12,14 -PGJ2 and Nogo. 2020 Mar 1
3 32290308 The Molecular Mechanisms Underlying Prostaglandin D2-Induced Neuritogenesis in Motor Neuron-Like NSC-34 Cells. 2020 Apr 10 1
4 31009317 Targeting Peroxisome Proliferator-Activated Receptor-Gamma Decreases Host Mortality After Influenza Infection in Obese Mice. 2019 May 1
5 31151271 An Algal Metabolite-Based PPAR-γ Agonist Displayed Anti-Inflammatory Effect via Inhibition of the NF-κB Pathway. 2019 May 30 4
6 31704099 15-Deoxy-Δ12,14-prostaglandin J2 ameliorates dextran sulfate sodium-induced colitis in mice through heme oxygenase-1 induction. 2019 Nov 30 2
7 30228306 15d-PGJ2-loaded nanocapsules ameliorate experimental gout arthritis by reducing pain and inflammation in a PPAR-gamma-sensitive manner in mice. 2018 Sep 18 3
8 28115365 Activation of PPARγ by endogenous prostaglandin J2 mediates the antileukemic effect of selenium in murine leukemia. 2017 Mar 30 1
9 28216619 15-Deoxy-Δ12,14-prostaglandin J2 alleviates hepatic ischemia-reperfusion injury in mice via inducing antioxidant response and inhibiting apoptosis and autophagy. 2017 May 1
10 27431935 Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ. 2016 Sep 2
11 26457076 15-Deoxy-Δ(12,14)-Prostaglandin J2 Inhibits Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury via Redox Pathway. 2015 4
12 24639050 CD200R1 and CD200 expression are regulated by PPAR-γ in activated glial cells. 2014 Jun 2
13 24698234 15-deoxy-Δ¹²,¹⁴-PGJ₂ promotes inflammation and apoptosis in cardiomyocytes via the DP2/MAPK/TNFα axis. 2014 May 15 1
14 24917395 Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism. 2014 Aug 5
15 25072357 Attenuation of IFN-γ-induced B7-H1 expression by 15-deoxy-delta(12,14)-prostaglandin J2 via downregulation of the Jak/STAT/IRF-1 signaling pathway. 2014 Sep 1 2
16 25120564 15-Deoxy- γ 12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPAR γ and Reduction in NF- κ B Activity. 2014 1
17 22917565 PPARγ ligand treatment inhibits cardiac inflammatory mediators induced by infection with different lethality strains of Trypanosoma cruzi. 2013 Jan 1
18 23397546 PPARγ ligand attenuates portal inflammation in the MRL-lpr mouse: a new strategy to restrain cholangiopathy in primary biliary cirrhosis. 2013 Sep 1
19 23542713 Activation of a retinoic acid receptor pathway by thiazolidinediones induces production of vascular endothelial growth factor/vascular permeability factor in OP9 adipocytes. 2013 May 5 1
20 23185633 PPARγ agonists promote oligodendrocyte differentiation of neural stem cells by modulating stemness and differentiation genes. 2012 1
21 22003398 15-Deoxy-Δ¹²,¹⁴ prostaglandin J₂ reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice. 2011 1
22 19922793 PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway. 2010 Mar 2
23 19752200 Peroxisome proliferator-activated receptor gamma antagonists decrease Na+ transport via the epithelial Na+ channel. 2009 Dec 1
24 18097063 Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway. 2008 Jan 1 3
25 18477501 Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor effects of troglitazone and 15-PGJ2. 2008 Sep 18 1
26 18671867 Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1. 2008 Jul 31 2
27 18691416 15-deoxy-delta12,14-prostaglandin J2 attenuates endothelial-monocyte interaction: implication for inflammatory diseases. 2008 Aug 8 3
28 17510607 THE PPARgamma ligand 15d-PGJ2 modulates macrophage activation after injury in a murine trauma model. 2007 Aug 2
29 18025192 Dose-dependent differential regulation of cytokine secretion from macrophages by fractalkine. 2007 Dec 1 1
30 16391825 Bacillus Calmette-Guérin induces the expression of peroxisome proliferator-activated receptor gamma in bladder cancer cells. 2006 Feb 1
31 16483373 The in vitro real-time oscillation monitoring system identifies potential entrainment factors for circadian clocks. 2006 Feb 16 3
32 16737695 15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells. 2006 Aug 1 1
33 15684285 Effect of rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 on bleomycin-induced lung injury. 2005 Feb 2
34 15868139 The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock. 2005 May 1
35 14742672 Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling. 2004 Feb 1
36 15137925 Fatty acid-mediated inhibition of IL-12 production by murine macrophages is independent of PPARgamma. 2004 May 1
37 12543809 The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs. 2003 Jan 15 2
38 12611492 Prostaglandin D2 synthase enzymes and PPARgamma are co-expressed in mouse 3T3-L1 adipocytes and human tissues. 2003 Jan 3
39 11927655 Regulation of murine macrophage proinflammatory and anti-inflammatory cytokines by ligands for peroxisome proliferator-activated receptor-gamma: counter-regulatory activity by IFN-gamma. 2002 Apr 1
40 11477074 Peroxisome proliferator-activated receptor gamma ligands differentially modulate muscle cell differentiation and MyoD gene expression via peroxisome proliferator-activated receptor gamma -dependent and -independent pathways. 2001 Oct 12 2
41 11728175 Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Delta(12,14)-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2. 2001 Oct 1
42 10623855 Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolysaccharide in vitro or in vivo. 2000 Jan 15 2
43 10640751 The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. 2000 Feb 1 3
44 10818446 PPAR-gamma-mediated regulation of normal and malignant B lineage cells. 2000 Apr 4
45 10868955 Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression. 2000 Mar 1