2,4-thiazolidinedione

peroxisome proliferator activated receptor gamma ; Mus musculus







139 Article(s)
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1 35013417 Different sites of actions make different responses to thiazolidinediones between mouse and rat models of fatty liver. 2022 Jan 10 3
2 35450368 Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation. 2022 Apr 14 1
3 33359401 Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease. 2021 Mar 1
4 34536928 Design, synthesis and bioactivity evaluation of thiazolidinedione derivatives as partial agonists targeting PPARγ. 2021 Nov 6
5 34707105 Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice. 2021 Oct 27 2
6 32630819 A Selective PPARγ Modulator Reduces Hepatic Fibrosis. 2020 Jul 2 2
7 32941798 Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3. 2020 Oct 6 1
8 32963510 Diet Modifies Pioglitazone's Influence on Hepatic PPARγ-Regulated Mitochondrial Gene Expression. 2020 4
9 33048436 Increased marrow adipogenesis does not contribute to age-dependent appendicular bone loss in female mice. 2020 Nov 3
10 33108252 Revisiting PPARγ as a new friend of GPR120 in the treatment of metabolic disorders. 2020 Dec 1
11 33137425 Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice. 2020 Dec 1
12 28895584 Effects of lobeglitazone, a novel thiazolidinedione, on adipose tissue remodeling and brown and beige adipose tissue development in db/db mice. 2018 Mar 1
13 29126303 Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid. 2018 Feb 1 1
14 29396370 Distinct adipocyte progenitor cells are associated with regional phenotypes of perivascular aortic fat in mice. 2018 Mar 1
15 29589839 PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. 2018 Jun 1 1
16 29979770 Effects of lobeglitazone on insulin resistance and hepatic steatosis in high-fat diet-fed mice. 2018 2
17 30121577 Inhibition of PPARγ, adipogenesis and insulin sensitivity by MAGED1. 2018 Nov 1 5
18 30145862 Effects of Three Thiazolidinediones on Metabolic Regulation and Cold-Induced Thermogenesis. 2018 Oct 31 1
19 30400642 Crosstalk between PPARγ Ligands and Inflammatory-Related Pathways in Natural T-Regulatory Cells from Type 1 Diabetes Mouse Model. 2018 Nov 5 2
20 30420515 PPARγ-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice. 2018 Nov 27 2
21 28027586 Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis. 2017 May 1
22 28219679 Thiazolidinediones abrogate cervical cancer growth. 2017 Apr 15 2
23 28263783 Establishment of a novel mouse model for pioglitazone-induced skeletal muscle injury. 2017 May 1 1
24 28597936 The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. 2017 Aug 1 4
25 28736228 DBZ is a putative PPARγ agonist that prevents high fat diet-induced obesity, insulin resistance and gut dysbiosis. 2017 Nov 1
26 28956370 Effects of Lobeglitazone, a New Thiazolidinedione, on Osteoblastogenesis and Bone Mineral Density in Mice. 2017 Sep 2
27 27325287 A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity. 2016 Sep 2
28 27374313 Activation of PPARγ by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage Polarization. 2016 Jul 1
29 27770626 Corrigendum to "Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice" [Neuroscience 302 (2015) 23-35]. 2016 Dec 17 1
30 27810934 Genetic Deletion of Neuronal PPARγ Enhances the Emotional Response to Acute Stress and Exacerbates Anxiety: An Effect Reversed by Rescue of Amygdala PPARγ Function. 2016 Dec 14 2
31 27981184 Pioglitazone, a PPARγ agonist rescues depression associated with obesity using chronic unpredictable mild stress model in experimental mice. 2016 Jun 2
32 25257948 An insulin-sensitizing thiazolidinedione, which minimally activates PPARγ, does not cause bone loss. 2015 Mar 6
33 25703056 Rosiglitazone ameliorates senescence-like phenotypes in a cellular photoaging model. 2015 Mar 1
34 25756249 Thiazolidinediones Inhibit Mouse Osteoblastic MC3T3-E1 Cell Proliferation in Part Through the Wnt Signaling Pathway. 2015 Jun 2
35 25907448 Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice. 2015 Aug 27 1
36 26183621 Selective targeting of PPARγ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency. 2015 Jul 17 4
37 26330489 Systemic PPARγ deletion causes severe disturbance in fluid homeostasis in mice. 2015 Nov 1
38 26362846 Rosiglitazone activation of PPARγ-dependent signaling is neuroprotective in mutant huntingtin expressing cells. 2015 Nov 1 2
39 26587016 Therapeutic Actions of the Thiazolidinediones in Alzheimer's Disease. 2015 2
40 24449420 Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts. 2014 Apr 2
41 24917675 Lipocalin 2 regulates brown fat activation via a nonadrenergic activation mechanism. 2014 Aug 8 1
42 25100724 A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity. 2014 Sep 19 2
43 23313309 Pioglitazone therapy in mouse offspring exposed to maternal obesity. 2013 Apr 1
44 23680913 Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARγ) agonist with potent glucose-lowering properties. 2013 Aug 1
45 23700717 Thiazolidinediones cause compaction of nuclear heterochromatin in the pluripotent mesenchymal cell line C3H10T1/2 when inducing an adipogenic phenotype. 2013 Apr 1
46 24079935 Pioglitazone counteracts the tumor necrosis factor-α inhibition of follicle-stimulating hormone-induced follicular development and estradiol production in an in vitro mouse preantral follicle culture system. 2013 Sep 30 2
47 21907283 PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease. 2012 Jan 2
48 22039047 Identification and mechanism of 10-carbon fatty acid as modulating ligand of peroxisome proliferator-activated receptors. 2012 Jan 2 1
49 22215652 Selective PPARγ modulator INT131 normalizes insulin signaling defects and improves bone mass in diet-induced obese mice. 2012 Mar 1 1
50 22333133 Diet supplementation with green tea extract epigallocatechin gallate prevents progression to glucose intolerance in db/db mice. 2012 Feb 14 1