Thiazolidinediones

peroxisome proliferator activated receptor gamma ; Mus musculus







171 Article(s)
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1 32428209 Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension. 2021 Jan 1 1
2 32845528 Sclerostin-Neutralizing Antibody Treatment Rescues Negative Effects of Rosiglitazone on Mouse Bone Parameters. 2021 Jan 1
3 33444819 Hepatocyte-Specific Loss of PPARγ Protects Mice From NASH and Increases the Therapeutic Effects of Rosiglitazone in the Liver. 2021 2
4 33955199 SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARγ2. 2021 Oct 2
5 34305596 Ectopic Overexpression of PPARγ2 in the Heart Determines Differences in Hypertrophic Cardiomyopathy After Treatment With Different Thiazolidinediones in a Mouse Model of Diabetes. 2021 1
6 31907999 Selective peroxisome proliferator-activated receptor-gamma modulator, INT131 exhibits anti-inflammatory effects in an EcoHIV mouse model. 2020 Feb 1
7 32814067 Enhancing insulin sensitivity by dual PPARγ partial agonist, β-catenin inhibitor: Design, synthesis of new αphthalimido-o-toluoyl2-aminothiazole hybrids. 2020 Oct 15 1
8 32941798 Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3. 2020 Oct 6 1
9 33192313 Pioglitazone Ameliorates Gentamicin Ototoxicity by Affecting the TLR and STAT Pathways in the Early Postnatal Organ of Corti. 2020 2
10 30606762 Endothelial Cell-Targeted Deletion of PPARγ Blocks Rosiglitazone-Induced Plasma Volume Expansion and Vascular Remodeling in Adipose Tissue. 2019 Mar 4
11 29589839 PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. 2018 Jun 1 3
12 29973382 Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors. 2018 Aug 1
13 30145862 Effects of Three Thiazolidinediones on Metabolic Regulation and Cold-Induced Thermogenesis. 2018 Oct 31 2
14 30320193 CMHX008, a PPARγ partial agonist, enhances insulin sensitivity with minor influences on bone loss. 2018 Sep 4
15 30569323 Novel glitazones as PPARγ agonists: molecular design, synthesis, glucose uptake activity and 3D QSAR studies. 2018 Dec 19 4
16 27023226 Astragaloside IV, a Natural PPARγ Agonist, Reduces Aβ Production in Alzheimer's Disease Through Inhibition of BACE1. 2017 May 1
17 28027586 Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis. 2017 May 1
18 28232477 Inhibition of Age-Related Therapy Resistance in Melanoma by Rosiglitazone-Mediated Induction of Klotho. 2017 Jun 15 1
19 28651330 Rosiglitazone Improves Insulin Resistance Mediated by 10,12 Conjugated Linoleic Acid in a Male Mouse Model of Metabolic Syndrome. 2017 Sep 1 1
20 28736228 DBZ is a putative PPARγ agonist that prevents high fat diet-induced obesity, insulin resistance and gut dysbiosis. 2017 Nov 1
21 28854981 Rosiglitazone increases endothelial cell migration and vascular permeability through Akt phosphorylation. 2017 Aug 30 3
22 28972081 Unique Interactome Network Signatures for Peroxisome Proliferator-activated Receptor Gamma (PPARγ) Modulation by Functional Selective Ligands. 2017 Dec 1
23 29202114 Dihydrosanguinarine Enhances Glucose Uptake in Mouse 3T3-L1 Cells. 2017 Oct 31 4
24 26858440 Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease. 2016 Feb 23 1
25 27138164 GQ-16, a TZD-Derived Partial PPARγ Agonist, Induces the Expression of Thermogenesis-Related Genes in Brown Fat and Visceral White Fat and Decreases Visceral Adiposity in Obese and Hyperglycemic Mice. 2016 1
26 27810934 Genetic Deletion of Neuronal PPARγ Enhances the Emotional Response to Acute Stress and Exacerbates Anxiety: An Effect Reversed by Rescue of Amygdala PPARγ Function. 2016 Dec 14 1
27 25409143 An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ. 2015 Jan 15 1
28 25531136 PPARγ agonist-induced fluid retention depends on αENaC expression in connecting tubules. 2015 2
29 25756249 Thiazolidinediones Inhibit Mouse Osteoblastic MC3T3-E1 Cell Proliferation in Part Through the Wnt Signaling Pathway. 2015 Jun 1
30 25827822 Identification of a novel selective agonist of PPARγ with no promotion of adipogenesis and less inhibition of osteoblastogenesis. 2015 Apr 1 2
31 25869519 New indole-thiazolidine attenuates atherosclerosis in LDLr(-/-) mice. 2015 Aug 4
32 25907448 Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice. 2015 Aug 27 1
33 25932594 Tributyltin engages multiple nuclear receptor pathways and suppresses osteogenesis in bone marrow multipotent stromal cells. 2015 Jun 15 1
34 25951943 The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice. 2015 May 8 5
35 26168725 PPARγ partial agonist GQ-16 strongly represses a subset of genes in 3T3-L1 adipocytes. 2015 Aug 28 4
36 26396687 Design, Synthesis, and Biological Evaluation of Indole Biphenylcarboxylic Acids as PPARγ Antagonists. 2015 Sep 10 2
37 24259440 PPARgamma agonist pioglitazone does not enhance performance in mice. 2014 Sep 1
38 24489087 PPAR-γ/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis. 2014 Mar 1 2
39 24882400 Search for new type of PPARγ agonist-like anti-diabetic compounds from medicinal plants. 2014 2
40 24982244 Inhibition of HDAC3 promotes ligand-independent PPARγ activation by protein acetylation. 2014 Oct 2
41 25051434 Overexpression of PPARγ specifically in pancreatic β-cells exacerbates obesity-induced glucose intolerance, reduces β-cell mass, and alters islet lipid metabolism in male mice. 2014 Oct 1
42 25064526 Retinaldehyde dehydrogenase 1 deficiency inhibits PPARγ-mediated bone loss and marrow adiposity. 2014 Oct 1
43 25100724 A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity. 2014 Sep 19 2
44 21153483 Thiazolidinediones protect mouse pancreatic β-cells directly from cytokine-induced cytotoxicity through PPARγ-dependent mechanisms. 2013 Apr 7
45 23542713 Activation of a retinoic acid receptor pathway by thiazolidinediones induces production of vascular endothelial growth factor/vascular permeability factor in OP9 adipocytes. 2013 May 5 2
46 23563205 Correlation between activation of PPARγ and resistin downregulation in a mouse adipocyte cell line by a series of thiazolidinediones. 2013 Aug 1
47 23563593 C333H ameliorated insulin resistance through selectively modulating peroxisome proliferator-activated receptor γ in brown adipose tissue of db/db mice. 2013 3
48 23891623 Cilostazol improves the response to ischemia in diabetic mice by a mechanism dependent on PPARγ. 2013 Dec 5 1
49 23946430 Pioglitazone does not improve insulin signaling in mice with GH over-expression. 2013 Nov 2
50 24005472 Increased susceptibility of db/db mice to rosiglitazone-induced plasma volume expansion: role of dysregulation of renal water transporters. 2013 Nov 15 4