Pioglitazone

peroxisome proliferator activated receptor gamma ; Mus musculus







304 Article(s)
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1 34341904 Preliminary evaluation of anticancer efficacy of pioglitazone combined with celecoxib for the treatment of non-small cell lung cancer. 2022 Feb 1
2 34856203 The PPARγ agonist pioglitazone produces a female-predominant inhibition of hyperalgesia associated with surgical incision, peripheral nerve injury, and painful diabetic neuropathy. 2022 Mar 1 2
3 35013417 Different sites of actions make different responses to thiazolidinediones between mouse and rat models of fatty liver. 2022 Jan 10 4
4 35072290 PPAR-γ agonist pioglitazone alleviates inflammatory response induced by lipopolysaccharides in osteoblast cells. 2022 Jan 24 2
5 35431893 Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition. 2022 2
6 35433953 The downregulation of miR-129-5p relieves the inflammatory response in acute respiratory distress syndrome by regulating PPARγ-mediated autophagy. 2022 Mar 1
7 35450368 Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation. 2022 Apr 14 1
8 35472412 Role of PPAR-γ in diabetes-induced testicular dysfunction, oxidative DNA damage and repair in leptin receptor-deficient obese type 2 diabetic mice. 2022 Jul 1 2
9 35490721 Peroxisome proliferator-activated receptor-γ ameliorates neuronal ferroptosis after traumatic brain injury in mice by inhibiting cyclooxygenase-2. 2022 Aug 1
10 35550871 Adipose Rheb deficiency promotes miR-182-5p expression via the cAMP/PPARγ signaling pathway. 2022 May 10 1
11 35628311 Regulation of Neuroinflammatory Signaling by PPARγ Agonist in Mouse Model of Diabetes. 2022 May 14 2
12 33015747 Pioglitazone modulates doxorubicin resistance in a in vivo model of drug resistant osteosarcoma xenograft. 2021 Feb 2
13 33197517 Dynamics of HOX gene expression and regulation in adipocyte development. 2021 Feb 5 1
14 33278514 Alcohol induces mitochondrial derangements in alveolar macrophages by upregulating NADPH oxidase 4. 2021 Feb 1
15 33359401 Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease. 2021 Mar 1
16 33577036 Effects of PPARγ agonist pioglitazone on cardiac fibrosis in diabetic mice by regulating PTEN/AKT/FAK pathway. 2021 Jan 5
17 33591571 Inactivation of SERCA2 Cys674 accelerates aortic aneurysms by suppressing PPARγ. 2021 Jun 1
18 33597848 PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice. 2021 2
19 33604775 Pioglitazone Attenuates Lupus Nephritis Symptoms in Mice by Modulating miR-21-5p/TIMP3 Axis: the Key Role of the Activation of Peroxisome Proliferator-Activated Receptor-γ. 2021 Aug 5
20 33754076 The role of GLS1-mediated glutaminolysis/2-HG/H3K4me3 and GSH/ROS signals in Th17 responses counteracted by PPARγ agonists. 2021 1
21 33781257 PPARγ activation improves the microenvironment of perivascular adipose tissue and attenuates aortic stiffening in obesity. 2021 Mar 29 2
22 33858491 N-acetyl cysteine induces quiescent-like pancreatic stellate cells from an active state and attenuates cancer-stroma interactions. 2021 Apr 15 1
23 34128467 Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ. 2021 Jun 15 1
24 34144391 Proteasome dysfunction under compromised redox metabolism dictates liver injury in NASH through ASK1/PPARγ binodal complementary modules. 2021 Sep 1
25 34412637 Post-treatment with the PPAR-γ agonist pioglitazone inhibits inflammation and bacterial growth during Klebsiella pneumonia. 2021 Aug 19 2
26 34522221 Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation. 2021 1
27 35111067 Peroxisome Proliferator-Activated Receptor-Gamma Reduces ER Stress and Inflammation via Targeting NGBR Expression. 2021 3
28 32015419 Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective. 2020 Feb 3 1
29 32260486 Pioglitazone-Mediated Peroxisome Proliferator-Activated Receptor γ Activation Aggravates Murine Immune-Mediated Hepatitis. 2020 Apr 5 3
30 32345753 Pharmacologic PPAR-γ Activation Reprograms Bone Marrow Macrophages and Partially Rescues HSPC Mobilization in Human and Murine Diabetes. 2020 Jul 2
31 32422516 PPARγ-mediated microglial activation phenotype is involved in depressive-like behaviors and neuroinflammation in stressed C57BL/6J and ob/ob mice. 2020 Jul 1
32 32665906 Activation of PPARγ Inhibits TLR4 Signal Transduction Pathway in Melanoma Cancer In Vitro. 2020 Jul 1
33 32676772 Further evidence for the involvement of the PPARγ system on alcohol intake and sensitivity in rodents. 2020 Oct 1
34 32963510 Diet Modifies Pioglitazone's Influence on Hepatic PPARγ-Regulated Mitochondrial Gene Expression. 2020 5
35 33105536 Effect of Pioglitazone on Perihematomal Edema in Intracerebral Hemorrhage Mouse Model by Regulating NLRP3 Expression and Energy Metabolism. 2020 Nov 1
36 33122687 Ischemia reperfusion-induced metastasis is resistant to PPARγ agonist pioglitazone in a murine model of colon cancer. 2020 Oct 29 1
37 33192313 Pioglitazone Ameliorates Gentamicin Ototoxicity by Affecting the TLR and STAT Pathways in the Early Postnatal Organ of Corti. 2020 2
38 30084995 Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte/macrophage polarization in preclinical animal models. 2019 Feb 1 2
39 30301961 Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity. 2019 Jun 1
40 30418546 Bitter Taste Receptor Ligand Improves Metabolic and Reproductive Functions in a Murine Model of PCOS. 2019 Jan 1 1
41 30507781 Pioglitazone, a PPARγ agonist, reduces cisplatin-evoked neuropathic pain by protecting against oxidative stress. 2019 Mar 3
42 30511276 Impact of elastin-derived VGVAPG peptide on bidirectional interaction between peroxisome proliferator-activated receptor gamma (Pparγ) and beta-galactosidase (β-Gal) expression in mouse cortical astrocytes in vitro. 2019 Apr 1
43 30594432 Identification of BR101549 as a lead candidate of non-TZD PPARγ agonist for the treatment of type 2 diabetes: Proof-of-concept evaluation and SAR. 2019 Feb 15 1
44 30623373 The Protective Role of Peroxisome Proliferator-Activated Receptor-Gamma in Seizure and Neuronal Excitotoxicity. 2019 Aug 1
45 30655107 Nanoparticle-mediated local delivery of pioglitazone attenuates bleomycin-induced skin fibrosis. 2019 Jan 1
46 30759294 The VGVAPG Peptide Regulates the Production of Nitric Oxide Synthases and Reactive Oxygen Species in Mouse Astrocyte Cells In Vitro. 2019 May 1
47 30816473 Pioglitazone increases VEGFR3 expression and promotes activation of M2 macrophages via the peroxisome proliferator‑activated receptor γ. 2019 Apr 4
48 30820023 Renal-Protective Effects of the Peroxisome Proliferator-Activated Receptor-γ Agonist Pioglitazone in ob/ob Mice. 2019 Mar 1 4
49 30867485 Low-dose pioglitazone can ameliorate learning and memory impairment in a mouse model of dementia by increasing LRP1 expression in the hippocampus. 2019 Mar 13 2
50 30957417 Resveratrol inhibits lipid accumulation in the intestine of atherosclerotic mice and macrophages. 2019 Jun 1