NAD

poly(ADP-ribose) polymerase 1 ; Homo sapiens







653 Article(s)
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1 34880123 cAMP-Mediated Autophagy Promotes Cell Survival via ROS-Induced Activation of PARP1: Implications for Treatment of Acute Lymphoblastic Leukemia. 2022 Mar 1 3
2 34926116 Pleiotropic role of PARP1: an overview. 2022 Jan 2
3 35203360 Maintenance of NAD+ Homeostasis in Skeletal Muscle during Aging and Exercise. 2022 Feb 17 4
4 35308855 Discovery of an NAD+ analogue with enhanced specificity for PARP1. 2022 Feb 16 5
5 35386537 Conceptual Framework for SARS-CoV-2-Related Lymphopenia. 2022 2
6 35410407 NAMPT-dependent NAD+ salvage is crucial for the decision between apoptotic and necrotic cell death under oxidative stress. 2022 Apr 11 3
7 35447104 Physiological levels of poly(ADP-ribose) during the cell cycle regulate HeLa cell proliferation. 2022 Aug 1 1
8 35479740 Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects. 2022 2
9 35545049 The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62. 2022 May 10 4
10 32402770 Histone-dependent PARP-1 inhibitors: A novel therapeutic modality for the treatment of prostate and renal cancers. 2021 Jun 1
11 33038343 Non-canonical roles of NAMPT and PARP in inflammation. 2021 Feb 2
12 33244652 Towards resolving the enigma of the dichotomy of resveratrol: cis- and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation. 2021 Jun 1
13 33387580 Poly (ADP-ribose) polymerase-1 as a promising drug target for neurodegenerative diseases. 2021 Feb 15 1
14 33450210 Mitochondrial NAD+ Controls Nuclear ARTD1-Induced ADP-Ribosylation. 2021 Jan 21 1
15 33481867 Fluorescent detection of PARP activity in unfixed tissue. 2021 2
16 33482196 Poly(ADP-ribose) polymerase 1 regulates mitochondrial DNA repair in an NAD-dependent manner. 2021 Jan-Jun 1
17 33485900 NAD+ and cardiovascular diseases. 2021 Apr 2
18 33524253 A Bifunctional NAD+ for Profiling Poly-ADP-Ribosylation-Dependent Interacting Proteins. 2021 Feb 19 2
19 33562281 Exogenous NAD+ Postpones the D-Gal-Induced Senescence of Bone Marrow-Derived Mesenchymal Stem Cells via Sirt1 Signaling. 2021 Feb 7 1
20 33657415 Avoid the trap: Targeting PARP1 beyond human malignancy. 2021 Apr 15 1
21 33683197 HPF1 and nucleosomes mediate a dramatic switch in activity of PARP1 from polymerase to hydrolase. 2021 Mar 8 1
22 33804735 The PARP Way to Epigenetic Changes. 2021 Mar 20 2
23 33811702 ATR prevents Ca2+ overload-induced necrotic cell death through phosphorylation-mediated inactivation of PARP1 without DNA damage signaling. 2021 May 1
24 33921561 Differences in PARP Inhibitors for the Treatment of Ovarian Cancer: Mechanisms of Action, Pharmacology, Safety, and Efficacy. 2021 Apr 19 3
25 33925170 Functional Roles of PARP2 in Assembling Protein-Protein Complexes Involved in Base Excision DNA Repair. 2021 Apr 28 1
26 34066057 PARP Power: A Structural Perspective on PARP1, PARP2, and PARP3 in DNA Damage Repair and Nucleosome Remodelling. 2021 May 12 1
27 34073600 Nicotinamide N-Methyltransferase in Acquisition of Stem Cell Properties and Therapy Resistance in Cancer. 2021 May 26 3
28 34115723 Repurposing of Clinically Approved Poly-(ADP-Ribose) Polymerase Inhibitors for the Therapy of Sepsis. 2021 Dec 1 1
29 34130091 Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. 2021 Aug 4
30 34342816 A375 melanoma cells are sensitized to cisplatin-induced toxicity by a synthetic nitro-flavone derivative 2-(4-Nitrophenyl)-4H-chromen-4-one through inhibition of PARP1. 2021 Aug 2
31 34380612 Single-molecule measurements reveal that PARP1 condenses DNA by loop stabilization. 2021 Aug 2
32 34445574 NMNAT1 Is a Survival Factor in Actinomycin D-Induced Osteosarcoma Cell Death. 2021 Aug 18 1
33 34485381 NAD+ Degrading Enzymes, Evidence for Roles During Infection. 2021 2
34 34619528 Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation. 2021 Nov 2
35 34629354 Okamoto model for necrosis and its expansions, CD38-cyclic ADP-ribose signal system for intracellular Ca2+ mobilization and Reg (Regenerating gene protein)-Reg receptor system for cell regeneration. 2021 3
36 34638458 Poly(ADP)-Ribosylation Inhibition: A Promising Approach for Clear Cell Renal Cell Carcinoma Therapy. 2021 Oct 3 3
37 34647721 Rapid Analysis of ADP-Ribosylation Dynamics and Site-Specificity Using TLC-MALDI. 2021 Nov 19 2
38 34663976 The alternative activity of nuclear PHGDH contributes to tumour growth under nutrient stress. 2021 Oct 1
39 34708032 Poly (ADP-Ribose) Polymerase 1 Regulates Cajal-Retzius Cell Development and Neural Precursor Cell Adhesion. 2021 1
40 34731617 Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis. 2021 Nov 2 2
41 34732825 Dual function of HPF1 in the modulation of PARP1 and PARP2 activities. 2021 Nov 3 1
42 34748530 NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death. 2021 Nov 2
43 34750509 Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency. 2021 Nov 8 1
44 34806016 NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells. 2021 Dec 2
45 34839666 Dual Imaging of Poly(ADP-ribose) Polymerase-1 and Endogenous H2O2 for the Diagnosis of Cancer Cells Using Silver-Coated Gold Nanorods. 2021 Dec 7 2
46 34919819 The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer. 2021 Dec 16 2
47 31782485 Mechanistic insight into the role of Poly(ADP-ribosyl)ation in DNA topology modulation and response to DNA damage. 2020 Feb 13 3
48 31855104 Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes. 2020 Mar 2
49 31959836 Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity. 2020 Jan 20 3
50 32028527 HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation. 2020 Mar 2