Ascorbic Acid

solute carrier family 2 member 1 ; Homo sapiens







44 Article(s)
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1 35142018 Harnessing GLUT1-Targeted Pro-oxidant Ascorbate for Synergistic Phototherapeutics. 2022 Apr 19 6
2 35626170 Ascorbate Plus Buformin in AML: A Metabolic Targeted Treatment. 2022 May 23 1
3 32008465 Vitamin C supplementation had no side effect in non-cancer, but had anticancer properties in ovarian cancer cells. 2021 Jun 1
4 33804775 High-Dose Vitamin C: Preclinical Evidence for Tailoring Treatment in Cancer Patients. 2021 Mar 20 1
5 34656060 Ascorbic acid ameliorates corneal endothelial dysfunction and enhances cell proliferation via the noncanonical GLUT1-ERK axis. 2021 Dec 1
6 32080778 Resveratrol potentiates intracellular ascorbic acid enrichment through dehydroascorbic acid transport and/or its intracellular reduction in HaCaT cells. 2020 Apr 1
7 30660746 Ascorbic acid-modified brain-specific liposomes drug delivery system with "lock-in" function. 2019 Nov 2
8 31857900 Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis: The electron transfer hypothesis. 2019 5
9 29371679 A functional interplay between Δ133p53 and ΔNp63 in promoting glycolytic metabolism to fuel cancer cell proliferation. 2018 Apr 1
10 29432735 Cellular toxicity driven by high-dose vitamin C on normal and cancer stem cells. 2018 Feb 26 1
11 29507622 Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation. 2018 9
12 30613280 Antitumoral effects of pharmacological ascorbate on gastric cancer cells: GLUT1 expression may not tell the whole story. 2018 1
13 27323830 Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer. 2016 Jul 26 1
14 26381034 Effect of Glucose on GLUT1-Dependent Intracellular Ascorbate Accumulation and Viability of Thyroid Cancer Cells. 2015 4
15 26541605 Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. 2015 Dec 11 1
16 24330097 The ROS-induced cytotoxicity of ascorbate is attenuated by hypoxia and HIF-1alpha in the NCI60 cancer cell lines. 2014 Mar 2
17 24598365 Human erythrocytes transport dehydroascorbic acid and sugars using the same transporter complex. 2014 May 15 1
18 24927052 Design, synthesis and biological evaluation of brain targeting l-ascorbic acid prodrugs of ibuprofen with "lock-in" function. 2014 Jul 23 2
19 23647458 Human choroid plexus papilloma cells efficiently transport glucose and vitamin C. 2013 Nov 1
20 23916956 Expression and/or activity of the SVCT2 ascorbate transporter may be decreased in many aggressive cancers, suggesting potential utility for sodium bicarbonate and dehydroascorbic acid in cancer therapy. 2013 Oct 1
21 22943001 Role of monosaccharide transport proteins in carbohydrate assimilation, distribution, metabolism, and homeostasis. 2012 Apr 1
22 23177992 Functional and physiological role of vitamin C transporters. 2012 2
23 22513420 Vitamin C and oxidative stress in the seminiferous epithelium. 2011 1
24 20494648 Cellular pathways for transport and efflux of ascorbate and dehydroascorbate. 2010 Aug 15 4
25 20570889 Low ascorbate levels are associated with increased hypoxia-inducible factor-1 activity and an aggressive tumor phenotype in endometrial cancer. 2010 Jul 15 1
26 19346941 Erythroid glucose transporters. 2009 May 3
27 18358804 Some vertebrates go with the GLO. 2008 Mar 21 2
28 18358815 Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C. 2008 Mar 21 2
29 18796630 The Glut1 and Glut4 glucose transporters are differentially expressed during perinatal and postnatal erythropoiesis. 2008 Dec 1 1
30 16731301 Enhanced expression of glucose transporter 1 on erythrocyte membrane in hemodialysis patients: the possible role in erythrocyte ascorbate recycling. 2006 Jun 4
31 15590689 6-Bromo-6-deoxy-L-ascorbic acid: an ascorbate analog specific for Na+-dependent vitamin C transporter but not glucose transporter pathways. 2005 Feb 18 2
32 16195374 Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury. 2005 Oct 4
33 15528049 Plasma membrane gamma-glutamyltransferase activity facilitates the uptake of vitamin C in melanoma cells. 2004 Dec 1 1
34 13129590 Glucose transporter type1 (GLUT-1) deficiency. 2003 Oct 1
35 12069599 Nicotinamide is not a substrate of the facilitative hexose transporter GLUT1. 2002 Jun 25 1
36 12166630 Recycling processes of cellular ascorbate generate oxidative stress in pancreatic tissues in in vitro system. 2002 Jun 2
37 12526083 Effects of glutamate on dehydroascorbate uptake and its enhanced vulnerability to the peroxidation in cerebral cortical slices. 2002 Dec 31 2
38 11170395 Direct inhibition of the hexose transporter GLUT1 by tyrosine kinase inhibitors. 2001 Jan 23 1
39 10801933 Intracellular accumulation of ascorbic acid is inhibited by flavonoids via blocking of dehydroascorbic acid and ascorbic acid uptakes in HL-60, U937 and Jurkat cells. 2000 May 1
40 10331392 A family of mammalian Na+-dependent L-ascorbic acid transporters. 1999 May 6 1
41 9708557 Deficient transport of dehydroascorbic acid in the glucose transporter protein syndrome. 1998 Aug 2
42 9389750 Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters. 1997 Dec 1 2
43 8783882 The mechanism of uptake of ascorbic acid into osteoblasts and leukocytes. 1996 May 1
44 7559541 Resolution of the facilitated transport of dehydroascorbic acid from its intracellular accumulation as ascorbic acid. 1995 Oct 6 2