Copper

synthesis of cytochrome C oxidase 1 ; Homo sapiens







34 Article(s)
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1 35053273 The Role of COA6 in the Mitochondrial Copper Delivery Pathway to Cytochrome c Oxidase. 2022 Jan 13 1
2 35210360 Mitochondrial COA7 is a heme-binding protein with disulfide reductase activity, which acts in the early stages of complex IV assembly. 2022 Mar 1 2
3 32061935 COA6 Facilitates Cytochrome c Oxidase Biogenesis as Thiol-reductase for Copper Metallochaperones in Mitochondria. 2020 Mar 27 2
4 31851937 COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase. 2019 Dec 17 3
5 31903891 Stable COX17 Downregulation Leads to Alterations in Mitochondrial Ultrastructure, Decreased Copper Content and Impaired Cytochrome c Oxidase Biogenesis in HEK293 Cells. 2019 1
6 29381136 COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis. 2018 Jan 30 1
7 28330871 Human mitochondrial cytochrome c oxidase assembly factor COX18 acts transiently as a membrane insertase within the subunit 2 maturation module. 2017 May 12 1
8 27516958 Transcriptome analysis of copper homeostasis genes reveals coordinated upregulation of SLC31A1,SCO1, and COX11 in colorectal cancer. 2016 Aug 1
9 25683716 The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis. 2015 Feb 17 4
10 26160915 COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2. 2015 Oct 1 1
11 24403053 Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase. 2014 Jun 1 1
12 23345593 COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux. 2013 Mar 11
13 21816817 Functional role of two interhelical disulfide bonds in human Cox17 protein from a structural perspective. 2011 Sep 30 2
14 20864674 Unexpected vascular enrichment of SCO1 over SCO2 in mammalian tissues: implications for human mitochondrial disease. 2010 Nov 1
15 19295170 Loss of function of Sco1 and its interaction with cytochrome c oxidase. 2009 May 5
16 18093982 A structural-dynamical characterization of human Cox17. 2008 Mar 21 2
17 18390903 Mapping the functional interaction of Sco1 and Cox2 in cytochrome oxidase biogenesis. 2008 May 30 1
18 18458339 Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer. 2008 May 13 4
19 17182746 Human Sco1 functional studies and pathological implications of the P174L mutant. 2007 Jan 2 3
20 17189203 The human cytochrome c oxidase assembly factors SCO1 and SCO2 have regulatory roles in the maintenance of cellular copper homeostasis. 2007 Jan 2
21 17244525 The scoop on Sco. 2007 Jan 26 1
22 17503777 A conserved cis-proline precludes metal binding by the active site thiolates in members of the thioredoxin family of proteins. 2007 Jun 12 1
23 16520371 The P174L mutation in human Sco1 severely compromises Cox17-dependent metallation but does not impair copper binding. 2006 May 5 4
24 16631971 Copper trafficking to the mitochondrion and assembly of copper metalloenzymes. 2006 Jul 2
25 16735468 A hint for the function of human Sco1 from different structures. 2006 Jun 6 1
26 15659396 Crystal structure of human SCO1: implications for redox signaling by a mitochondrial cytochrome c oxidase "assembly" protein. 2005 Apr 15 2
27 15707358 Ortholog search of proteins involved in copper delivery to cytochrome C oxidase and functional analysis of paralogs and gene neighbors by genomic context. 2005 Jan-Feb 1
28 16091356 Human Sco1 and Sco2 function as copper-binding proteins. 2005 Oct 7 4
29 15199057 Specific copper transfer from the Cox17 metallochaperone to both Sco1 and Cox11 in the assembly of yeast cytochrome C oxidase. 2004 Aug 20 5
30 15229189 Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase. 2004 Sep 1 4
31 12788943 Mutagenesis reveals a specific role for Cox17p in copper transport to cytochrome oxidase. 2003 Aug 15 2
32 10954195 Cytochrome c oxidase assembly factors with a thioredoxin fold are conserved among prokaryotes and eukaryotes. 2000 5
33 11013136 Mutations of the SCO1 gene in mitochondrial cytochrome c oxidase deficiency with neonatal-onset hepatic failure and encephalopathy. 2000 Nov 1
34 11027508 Characterization of human SCO1 and COX17 genes in mitochondrial cytochrome-c-oxidase deficiency. 2000 Sep 24 1