Fatty Acids

acetyl-CoA carboxylase alpha ; Homo sapiens







84 Article(s)
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1 34028877 Acetyl-CoA carboxylase-1/2 blockade locks dendritic cells in the semimature state associated with FA deprivation by favoring FAO. 2022 Mar 2
2 34743295 Constituents of Morus alba var. multicaulis leaf improve lipid metabolism by activating the AMPK signaling pathway in HepG2 cells. 2022 Jan 1
3 34981667 Increased mitochondrial fission drives the reprogramming of fatty acid metabolism in hepatocellular carcinoma cells through suppression of Sirtuin 1. 2022 Jan 1
4 35051863 The Alzheimer's disease drug candidate J147 decreases blood plasma fatty acid levels via modulation of AMPK/ACC1 signaling in the liver. 2022 Mar 1
5 35121743 Synthetic adiponectin-receptor agonist, AdipoRon, induces glycolytic dependence in pancreatic cancer cells. 2022 Feb 4 2
6 35162967 Quercetin Reduces Lipid Accumulation in a Cell Model of NAFLD by Inhibiting De Novo Fatty Acid Synthesis through the Acetyl-CoA Carboxylase 1/AMPK/PP2A Axis. 2022 Jan 18 2
7 35215774 SGIV Induced and Exploited Cellular De Novo Fatty Acid Synthesis for Virus Entry and Replication. 2022 Jan 18 1
8 35359351 Acetyl-CoA Carboxylases and Diseases. 2022 1
9 35449157 USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma. 2022 Apr 21 2
10 33199826 A novel metabolic function of Myc in regulation of fatty acid synthesis in prostate cancer. 2021 Jan 1
11 33414447 MIEF2 reprograms lipid metabolism to drive progression of ovarian cancer through ROS/AKT/mTOR signaling pathway. 2021 Jan 5 1
12 34258288 Impact of Adenosine Analogue, Adenosine-5'-N-Ethyluronamide (NECA), on Insulin Signaling in Skeletal Muscle Cells. 2021 1
13 34458145 Fatty Acid Metabolism-Related lncRNAs Are Potential Biomarkers for Predicting the Overall Survival of Patients With Colorectal Cancer. 2021 1
14 32106265 Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells. 2020 Feb 1
15 32470050 Pyrrolocin C and equisetin inhibit bacterial acetyl-CoA carboxylase. 2020 2
16 32670813 Withania somnifera root extract inhibits fatty acid synthesis in prostate cancer cells. 2020 May 2
17 33232284 Loss of FBP1 promotes proliferation, migration, and invasion by regulating fatty acid metabolism in esophageal squamous cell carcinoma. 2020 Nov 21 1
18 33343508 ChREBP-Mediated Regulation of Lipid Metabolism: Involvement of the Gut Microbiota, Liver, and Adipose Tissue. 2020 1
19 30781698 Chronic Hypoxia Enhances β-Oxidation-Dependent Electron Transport via Electron Transferring Flavoproteins. 2019 Feb 18 1
20 30816537 ACC1 is overexpressed in liver cancers and contributes to the proliferation of human hepatoma Hep G2 cells and the rat liver cell line BRL 3A. 2019 May 2
21 30899433 Prolyl isomerase Pin1 binds to and stabilizes acetyl CoA carboxylase 1 protein, thereby supporting cancer cell proliferation. 2019 Feb 26 4
22 30950477 The intriguing chemistry and biology of soraphens. 2019 Oct 1 1
23 30999821 Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models. 2019 1
24 31155494 CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress. 2019 Jul 2 1
25 31325544 Synthesis and anti-cancer activity of ND-646 and its derivatives as acetyl-CoA carboxylase 1 inhibitors. 2019 Sep 1 2
26 29208696 Acetyl-CoA carboxylase 1 regulates endothelial cell migration by shifting the phospholipid composition. 2018 Feb 2
27 29343429 Translational control of human acetyl-CoA carboxylase 1 mRNA is mediated by an internal ribosome entry site in response to ER stress, serum deprivation or hypoxia mimetic CoCl2. 2018 Apr 2
28 29675017 De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages. 2018 1
29 29899443 Structural basis for regulation of human acetyl-CoA carboxylase. 2018 Jun 1
30 27750213 Acetyl-CoA carboxylase inhibitors attenuate WNT and Hedgehog signaling and suppress pancreatic tumor growth. 2017 Jul 25 1
31 27983949 Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation. 2017 Jan 1 2
32 28259683 Inhibition of Sebum Production with the Acetyl Coenzyme A Carboxylase Inhibitor Olumacostat Glasaretil. 2017 Jul 2
33 28848043 Fatty acid synthase regulates the pathogenicity of Th17 cells. 2017 Nov 1
34 27113332 Transcriptional regulation of acetyl-CoA carboxylase α isoforms in dairy ewes during conjugated linoleic acid induced milk fat depression. 2016 Oct 2
35 27592350 Trans10,cis15 18:2 Isolated from Beef Fat Does Not Have the Same Anti-Adipogenic Properties as Trans10,cis12-18:2 in 3T3-L1 Adipocytes. 2016 Nov 1
36 25979092 The acetyl-CoA carboxylase enzyme: a target for cancer therapy? 2015 Jun 2
37 26632252 MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1. 2015 Dec 3 1
38 26690487 Obesity-Related Chronic Kidney Disease-The Role of Lipid Metabolism. 2015 Dec 11 2
39 24567531 Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity. 2014 Apr 1 1
40 25282359 De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells. 2014 Nov 3
41 23486665 Inhibition of rotavirus replication by downregulation of fatty acid synthesis. 2013 Jun 2
42 23777347 Disentangling two QTL on porcine chromosome 12 for backfat fatty acid composition. 2013 1
43 24277613 Spot14/Mig12 heterocomplex sequesters polymerization and restrains catalytic function of human acetyl-CoA carboxylase 2. 2013 Dec 1
44 22238651 Metabolic regulation of invadopodia and invasion by acetyl-CoA carboxylase 1 and de novo lipogenesis. 2012 3
45 22457791 SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids. 2012 2
46 22660331 AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress. 2012 May 9 2
47 22718502 The SNPs in the ACACA gene are effective on fatty acid composition in Holstein milk. 2012 Sep 2
48 21184748 Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation. 2011 Mar 1 1
49 21525791 TOFA (5-tetradecyl-oxy-2-furoic acid) reduces fatty acid synthesis, inhibits expression of AR, neuropilin-1 and Mcl-1 and kills prostate cancer cells independent of p53 status. 2011 Jul 1 3
50 22012398 Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. 2011 Oct 19 1