temsirolimus

mechanistic target of rapamycin kinase ; Mus musculus







22 Article(s)
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Pub. Year
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1 31714543 Tumor regression and potentiation of polymeric vascular disrupting therapy through reprogramming of a hypoxia microenvironment with temsirolimus. 2020 Jan 1 1
2 30087612 Therapeutic Effect of Repurposed Temsirolimus in Lung Adenocarcinoma Model. 2018 1
3 27863926 Combination of temsirolimus and adriamycin exhibits an enhanced antitumor effect in hepatocellular carcinoma. 2017 Mar 1
4 28631253 Portal branch ligation does not counteract the inhibiting effect of temsirolimus on extrahepatic colorectal metastatic growth. 2017 Jun 2
5 27662658 Synergistic activity of ALK and mTOR inhibitors for the treatment of NPM-ALK positive lymphoma. 2016 Nov 8 1
6 25408212 Rapamycin ester analog CCI-779/Temsirolimus alleviates tau pathology and improves motor deficit in mutant tau transgenic mice. 2015 4
7 25808836 Targeting Survivin Inhibits Renal Cell Carcinoma Progression and Enhances the Activity of Temsirolimus. 2015 Jun 1
8 26245309 Temsirolimus targets multiple hallmarks of cancer to impede mesothelioma growth in vivo. 2015 Nov 1
9 24493623 Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism. 2014 Apr 1
10 24793166 Temsirolimus induces surfactant lipid accumulation and lung inflammation in mice. 2014 Jun 15 1
11 23291985 Antiproliferative effect of a novel mTOR inhibitor temsirolimus contributes to the prolonged survival of orthotopic esophageal cancer-bearing mice. 2013 Mar 3
12 23358238 Dissociation of the pharmacological effects of THC by mTOR blockade. 2013 Jun 2
13 23872603 Carbamazepine promotes liver regeneration and survival in mice. 2013 Dec 1
14 23936035 Augmenting autophagy to treat acute kidney injury during endotoxemia in mice. 2013 1
15 21394501 The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models. 2012 Jan 1
16 21285988 Temsirolimus, an mTOR inhibitor, enhances anti-tumour effects of heat shock protein cancer vaccines. 2011 Feb 15 1
17 21521416 Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells. 2011 Jul 3
18 21673053 A low carbohydrate, high protein diet slows tumor growth and prevents cancer initiation. 2011 Jul 1 1
19 21718677 The mTOR/AKT inhibitor temsirolimus prevents deep infiltrating endometriosis in mice. 2011 Aug 2
20 16341243 Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer. 2006 Jan 1
21 15833854 Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras. 2005 Apr 15 1
22 14534328 mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. 2003 Oct 28 1