Oxysterols

3-hydroxy-3-methylglutaryl-CoA reductase ; Homo sapiens







12 Article(s)
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#Total Relationships
1 32616181 Bisphosphonate esters interact with HMG-CoA reductase membrane domain to induce its degradation. 2020 Jul 15 3
2 31580889 Side-chain oxysterols suppress the transcription of CTP: Phosphoethanolamine cytidylyltransferase and 3-hydroxy-3-methylglutaryl-CoA reductase by inhibiting the interaction of p300 and NF-Y, and H3K27 acetylation. 2019 Dec 1
3 18996837 Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions. 2009 Jan 16 1
4 18502209 Sterol regulators of cholesterol homeostasis and beyond: the oxysterol hypothesis revisited and revised. 2008 Nov 1
5 17393208 Syntheses of ring C oxysterols: inhibitors of sterol biosynthesis. 2007 Feb 1
6 8820110 Effects of a novel 2,3-oxidosqualene cyclase inhibitor on the regulation of cholesterol biosynthesis in HepG2 cells. 1996 Jan 1
7 7791533 Side-chain oxysterol regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. 1995 Mar 1
8 7797494 Low density lipoprotein (LDL) cholesterol is converted to 27-hydroxycholesterol in human fibroblasts. Evidence that 27-hydroxycholesterol can be an important intracellular mediator between LDL and the suppression of cholesterol production. 1995 Jun 23 1
9 8057282 Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription. 1994 Jul 22 1
10 1329783 The effect of 25-hydroxycholesterol on the regulation of apolipoprotein E mRNA levels and secretion in the human hepatoma HepG2. 1992 Aug 1
11 1352965 Correlation among oxysterol potencies in the regulation of the degradation of 3-hydroxy-3-methylglutaryl CoA reductase, the repression of 3-hydroxy-3-methylglutaryl CoA synthase and affinities for the oxysterol receptor. 1992 Jul 15 1
12 3382396 6-Nitrocholesterol inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase and tumor cell growth. 1988 Jun 16 1