prostaglandin E receptor 4 ; Rattus norvegicus

96 Article(s)
Pub. Year
#Total Relationships
1 35550162 The EP3 and EP4 Receptor Subtypes both Mediate the Fever-producing Effects of Prostaglandin E2 in the Rostral Ventromedial Preoptic Area of the Hypothalamus in Rats. 2022 May 10 1
2 33049240 Localization of prostaglandin E2 synthases and E-prostanoid receptors in the spinal cord in a rat model of neuropathic pain. 2021 Jan 1 1
3 33370588 The PGE2 receptor EP3 plays a positive role in the activation of hypothalamic-pituitary-adrenal axis and neuronal activity in the hypothalamus under immobilization stress. 2021 Mar 2
4 33410110 A Novel Second-Generation EP2 Receptor Antagonist Reduces Neuroinflammation and Gliosis After Status Epilepticus in Rats. 2021 Apr 2
5 33622238 Role of PGE2 in colonic motility: PGE2 attenuates spontaneous contractions of circular smooth muscle via EP4 receptors in the rat colon. 2021 Feb 23 1
6 33822473 Prostaglandin E2 induced cardiac hypertrophy through EP2 receptor-dependent activation of β-catenin in 5/6 nephrectomy rats. 2021 Jun 2
7 34003864 Inhibitory effects of a selective prostaglandin E2 receptor antagonist RQ-15986 on inflammation-related colon tumorigenesis in APC-mutant rats. 2021 1
8 30643209 CP-25 reverses prostaglandin E4 receptor desensitization-induced fibroblast-like synoviocyte dysfunction via the G protein-coupled receptor kinase 2 in autoimmune arthritis. 2019 Aug 2
9 30771056 Regulatory effects of paeoniflorin-6'-O-benzene sulfonate (CP-25) on dendritic cells maturation and activation via PGE2-EP4 signaling in adjuvant-induced arthritic rats. 2019 Oct 2
10 31166645 The role of prostaglandin and E series prostaglandin receptor type 4 receptors in the development of bladder overactivity in a rat model of chemically induced prostatic inflammation. 2019 Nov 1
11 31189158 Beraprost Upregulates KV Channel Expression and Function via EP4 Receptor in Pulmonary Artery Smooth Muscle Cells Obtained from Rats with Hypoxia-Induced Pulmonary Hypertension. 2019 1
12 31297954 Inhibition of prostaglandin E2 receptor 4 by lnc000908 to promote the endothelial-mesenchymal transition participation in cardiac remodelling. 2019 Sep 1
13 31513790 Enhancement of acid-sensing ion channel activity by prostaglandin E2 in rat dorsal root ganglion neurons. 2019 Dec 1 2
14 31818003 GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice. 2019 Dec 8 1
15 29336505 Signalling transduction events involved in agonist-induced PGE2/EP4 receptor externalization in cultured rat dorsal root ganglion neurons. 2018 May 3
16 29527151 Protective Effects of L-902,688, a Prostanoid EP4 Receptor Agonist, against Acute Blood-Brain Barrier Damage in Experimental Ischemic Stroke. 2018 1
17 30076448 Pharmacological properties of ASP7657, a novel, potent, and selective prostaglandin EP4 receptor antagonist. 2018 Dec 1
18 28228071 A Rat Model of Ischemic Enteritis: Pathogenic Importance of Enterobacteria, iNOS/NO, and COX-2/PGE2. 2017 2
19 28736136 Prostaglandin E2 modulates presynaptic regulation of GnRH neurons via EP4 receptors in accordance with estrogen milieu. 2017 Sep 30 3
20 28761141 Effects of pulpotomy using mineral trioxide aggregate on prostaglandin transporter and receptors in rat molars. 2017 Jul 31 2
21 27000064 Antidiuretic Action of Collecting Duct (Pro)Renin Receptor Downstream of Vasopressin and PGE2 Receptor EP4. 2016 Oct 1
22 27111625 Study on Physiological Roles of Stimulation of Prostaglandin E2 Receptor Subtype EP2 in Urethral Function in Rats. 2016 May 1
23 27400965 Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A. 2016 Jul 11 3
24 27435772 [Media of rat macrophage NR8383 cells with prostaglandins E2-induced VEGF over-expression promotes migration and tube formation of human umbilical vein endothelial cells]. 2016 Jun 20 1
25 27478311 Simultaneous Inhibition of PGE2 and PGI2 Signals Is Necessary to Suppress Hyperalgesia in Rat Inflammatory Pain Models. 2016 1
26 27535007 Augmented oxidative stress and preserved vasoconstriction induced by hydrogen peroxide in coronary arteries in obesity: role of COX-2. 2016 Nov 1
27 25446121 Prostaglandin potentiates 5-HT responses in stomach and ileum innervating visceral afferent sensory neurons. 2015 Jan 2 1
28 26051129 Time-dependent changes in inhibitory action of lipopolysaccharide on intestinal motility in rat. 2015 Nov 3
29 26311764 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. 2015 Aug 26 1
30 26445960 Mechanism of QSYQ on anti-apoptosis mediated by different subtypes of cyclooxygenase in AMI induced heart failure rats. 2015 Oct 7 2
31 26469753 Doxycycline Attenuates Endotoxin-Induced Uveitis by Prostaglandin E2-EP4 Signaling. 2015 Oct 2
32 25263346 PGE2 reduces MMP-14 and increases plasminogen activator inhibitor-1 in cardiac fibroblasts. 2014 Oct 4
33 23220160 Modulation of antigen-induced responses by serotonin and prostaglandin E2 via EP1 and EP4 receptors in the peripheral rat lung. 2013 Jan 15 1
34 23478083 Suppression of acute rejection by administration of prostaglandin E2 receptor subtype 4 agonist in rat organ transplantation models. 2013 Aug 1
35 24013220 Regulation of rat intrapulmonary arterial tone by arachidonic acid and prostaglandin E2 during hypoxia. 2013 1
36 22257560 Prostaglandin receptors EP and FP are regulated by estradiol and progesterone in the uterus of ovariectomized rats. 2012 Jan 18 1
37 22309829 Prostaglandin E2 contributes to the synthesis of brain-derived neurotrophic factor in primary sensory neuron in ganglion explant cultures and in a neuropathic pain model. 2012 Apr 1
38 22452546 Mechanisms and urodynamic effects of a potent and selective EP4 receptor antagonist, MF191, on cyclophosphamide and prostaglandin E2-induced bladder overactivity in rats. 2012 Nov 2
39 22546206 Synthesis and evaluation of γ-lactam analogs of PGE₂ as EP4 and EP2/EP4 agonists. 2012 Jun 1 2
40 21371033 Role of prostaglandin E2 in the synthesis of the pro-inflammatory cytokine interleukin-6 in primary sensory neurons: an in vivo and in vitro study. 2011 Sep 3
41 21549696 Glial cells isolated from dorsal root ganglia express prostaglandin E(2) (EP(4)) and prostacyclin (IP) receptors. 2011 Jul 1 1
42 20552550 Involvement of endogenous prostaglandin E2 in tubular epithelial regeneration through inhibition of apoptosis and epithelial-mesenchymal transition in cisplatin-induced rat renal lesions. 2010 Aug 5
43 20586869 Endogenous prostaglandin E2 accelerates healing of indomethacin-induced small intestinal lesions through upregulation of vascular endothelial growth factor expression by activation of EP4 receptors. 2010 May 1
44 19233324 EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures. 2009 Jun 1
45 19679653 Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of Leydig tumor cells. 2009 Oct 16 2
46 18031725 Effect of prostanoid EP4 receptor antagonist, CJ-042,794, in rat models of pain and inflammation. 2008 Feb 2 1
47 18498708 Effects of the selective EP4 antagonist, CJ-023,423 on chronic inflammation and bone destruction in rat adjuvant-induced arthritis. 2008 Jun 1
48 18726914 Identification of prostaglandin E2 receptors mediating perinatal masculinization of adult sex behavior and neuroanatomical correlates. 2008 Oct 2
49 17067562 Prostaglandin E2 activates Stat3 in neonatal rat ventricular cardiomyocytes: A role in cardiac hypertrophy. 2007 Jan 1 2
50 17408863 Exploration of prostanoid receptor subtype regulating estradiol and prostaglandin E2 induction of spinophilin in developing preoptic area neurons. 2007 May 25 1