| Protein Name | thiopurine S-methyltransferase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 690050 |
| Gene Symbol | Tpmt |
| UniProt | Q9Z0T0 (TPMT_RAT), B0BMT6 (B0BMT6_RAT), Q7TP19 (Q7TP19_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
3
Total Number of Articles : 2 |
Description |
thiopurine S-methyltransferase |
| Gene Summary |
Predicted to enable S-adenosyl-L-methionine binding activity and thiopurine S-methyltransferase activity. Involved in response to testosterone. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and poor metabolism of thiopurines 1. Orthologous to human TPMT (thiopurine S-methyltransferase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |