Protein Name thiopurine S-methyltransferase
Organism Rattus norvegicus
Gene ID 690050
Gene Symbol

Tpmt

UniProt Q9Z0T0 (TPMT_RAT), B0BMT6 (B0BMT6_RAT), Q7TP19 (Q7TP19_RAT)
Relationships Total Number of functionally related compound(s) : 3
Total Number of Articles : 2
Description

thiopurine S-methyltransferase

Gene Summary

Predicted to enable S-adenosyl-L-methionine binding activity and thiopurine S-methyltransferase activity. Involved in response to testosterone. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and thiopurine S-methyltransferase deficiency. Orthologous to human TPMT (thiopurine S-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • thiopurine S-methyltransferase
  • thiopurine methyltransferase
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Properties