Protein Name hes family bHLH transcription factor 1
Organism Rattus norvegicus
Gene ID 29577
Gene Symbol

Hes1

UniProt Q04666 (HES1_RAT)
Relationships Total Number of functionally related compound(s) : 78
Total Number of Articles : 76
Description

hes family bHLH transcription factor 1

Gene Summary

Enables several functions, including JUN kinase binding activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in several processes, including cellular response to cytokine stimulus; generation of neurons; and regulation of gene expression. Located in chromatin and nuclear matrix. Used to study chronic myeloid leukemia and epilepsy. Biomarker of acute kidney failure. Orthologous to human HES1 (hes family bHLH transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • transcription factor HES-1
  • RHL
  • hairy and enhancer of split 1
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Properties