Protein Name fibroblast growth factor 3
Organism Homo sapiens
Gene ID 2248
Gene Symbol

FGF3

UniProt P11487 (FGF3_HUMAN)
Relationships Total Number of functionally related compound(s) : 51
Total Number of Articles : 52
Description

fibroblast growth factor 3

Gene Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008]

synonyms
  • fibroblast growth factor 3
  • FGF-3
  • INT-2 proto-oncogene protein
Click to show/hide the synonyms
Properties