Protein Name semenogelin 2
Organism Homo sapiens
Gene ID 6407
Gene Symbol


UniProt Q02383 (SEMG2_HUMAN)
Relationships Total Number of functionally related compound(s) : 17
Total Number of Articles : 12

semenogelin 2

Gene Summary

The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015]

  • semenogelin-2
  • semenogelin II
  • SGII
Click to show/hide the synonyms