Protein Name chaperonin containing TCP1 subunit 4
Organism Homo sapiens
Gene ID 10575
Gene Symbol

CCT4

UniProt P50991 (TCPD_HUMAN)
Relationships Total Number of functionally related compound(s) : 264
Total Number of Articles : 257
Description

chaperonin containing TCP1 subunit 4

Gene Summary

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]

synonyms
  • T-complex protein 1 subunit delta
  • TCP-1-delta
  • chaperonin containing T-complex polypeptide 1 subunit 4
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Properties