| Protein Name | deoxyhypusine synthase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1725 |
| Gene Symbol | DHPS |
| UniProt | P49366 (DHYS_HUMAN), A0A024R7E9 (A0A024R7E9_HUMAN), A0A024R7D0 (A0A024R7D0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
181
Total Number of Articles : 179 |
Description |
deoxyhypusine synthase |
| Gene Summary |
This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011] |
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| Properties | |