Protein Name deoxyhypusine synthase
Organism Homo sapiens
Gene ID 1725
Gene Symbol


UniProt P49366 (DHYS_HUMAN), A0A024R7E9 (A0A024R7E9_HUMAN), A0A024R7D0 (A0A024R7D0_HUMAN)
Relationships Total Number of functionally related compound(s) : 181
Total Number of Articles : 179

deoxyhypusine synthase

Gene Summary

This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011]

  • deoxyhypusine synthase
  • migration-inducing gene 13
  • DHS
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