Protein Name solute carrier family 18 (vesicular monoamine), member 2
Organism Mus musculus
Gene ID 214084
Gene Symbol

Slc18a2

UniProt Q8BRU6 (VMAT2_MOUSE)
Relationships Total Number of functionally related compound(s) : 100
Total Number of Articles : 158
Description

solute carrier family 18 (vesicular monoamine), member 2

Gene Summary

Predicted to enable several functions, including amine transmembrane transporter activity; heat shock protein binding activity; and serotonin:sodium symporter activity. Involved in neurotransmitter loading into synaptic vesicle. Acts upstream of or within several processes, including locomotory behavior; response to amphetamine; and response to toxic substance. Located in dopaminergic synapse. Is expressed in several structures, including adrenal gland; alimentary system; eye; integumental system; and nervous system. Human ortholog(s) of this gene implicated in Parkinson's disease and type 1 diabetes mellitus. Orthologous to human SLC18A2 (solute carrier family 18 member A2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • synaptic vesicular amine transporter
  • VAT2
  • monoamine transporter
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Properties