Protein Name aminolevulinate, delta-, dehydratase
Organism Mus musculus
Gene ID 17025
Gene Symbol


UniProt P10518 (HEM2_MOUSE), Q9DD05 (Q9DD05_MOUSE)
Relationships Total Number of functionally related compound(s) : 57
Total Number of Articles : 47

aminolevulinate, delta-, dehydratase

Gene Summary

Enables identical protein binding activity and porphobilinogen synthase activity. Acts upstream of or within cellular response to interleukin-4 and heme biosynthetic process. Predicted to be located in extracellular space. Predicted to be active in cytosol. Is expressed in several structures, including liver; lung; metanephros; spleen; and yolk sac. Human ortholog(s) of this gene implicated in porphyria cutanea tarda and sickle cell anemia. Orthologous to human ALAD (aminolevulinate dehydratase). [provided by Alliance of Genome Resources, Apr 2022]

  • delta-aminolevulinic acid dehydratase
  • porphobilinogen synthase
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