Protein Name 3-isopropylmalate dehydratase LEU1
Organism Saccharomyces cerevisiae S288C
Gene ID 852875
Gene Symbol

LEU1

UniProt P07264 (LEUC_YEAST)
Relationships Total Number of functionally related compound(s) : 19
Total Number of Articles : 23
Description

3-isopropylmalate dehydratase LEU1

Gene Summary

Enables 3-isopropylmalate dehydratase activity. Involved in leucine biosynthetic process. Located in cytosol. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human ACO1 (aconitase 1) and IREB2 (iron responsive element binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • 3-isopropylmalate dehydratase LEU1
  • YGL009C
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Properties