Protein Name OTU domain containing 7B
Organism Mus musculus
Gene ID 229603
Gene Symbol

Otud7b

UniProt B2RUR8 (OTU7B_MOUSE)
Relationships Total Number of functionally related compound(s) : 1
Total Number of Articles : 1
Description

OTU domain containing 7B

Gene Summary

Enables K63-linked polyubiquitin modification-dependent protein binding activity and cysteine-type deubiquitinase activity. Involved in several processes, including negative regulation of canonical NF-kappaB signal transduction; negative regulation of transcription by RNA polymerase II; and protein K48-linked deubiquitination. Acts upstream of or within in utero embryonic development and protein deubiquitination. Located in cytoplasm. Orthologous to human OTUD7B (OTU deubiquitinase 7B). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • OTU domain-containing protein 7B
  • TRAF binding domain containing 2
  • cellular zinc finger anti-NF-kappa-B protein
Click to show/hide the synonyms
Properties