Protein Name kallikrein 1-related peptidase C12
Organism Rattus norvegicus
Gene ID 292855
Gene Symbol

Klk1c12

UniProt F1LNH4 (F1LNH4_RAT)
Relationships Total Number of functionally related compound(s) : 31
Total Number of Articles : 19
Description

kallikrein 1-related peptidase C12

Gene Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in regulation of systemic arterial blood pressure and zymogen activation. Predicted to be active in extracellular space and secretory granule. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • glandular kallikrein-12, submandibular/renal
  • glandular kallikrein-7, submandibular/renal
  • kallikrein 1
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Properties