Protein Name alpha 1,4-galactosyltransferase (P1PK blood group)
Organism Homo sapiens
Gene ID 53947
Gene Symbol

A4GALT

UniProt Q9NPC4 (A4GAT_HUMAN), A0A0S2Z5J1 (A0A0S2Z5J1_HUMAN)
Relationships Total Number of functionally related compound(s) : 253
Total Number of Articles : 481
Description

alpha 1,4-galactosyltransferase (P1PK blood group)

Gene Summary

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]

synonyms
  • lactosylceramide 4-alpha-galactosyltransferase
  • CD77 synthase
  • GB3 synthase
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Properties