Protein Name proprotein convertase subtilisin/kexin type 4
Organism Mus musculus
Gene ID 18551
Gene Symbol

Pcsk4

UniProt P29121 (PCSK4_MOUSE)
Relationships Total Number of functionally related compound(s) : 23
Total Number of Articles : 18
Description

proprotein convertase subtilisin/kexin type 4

Gene Summary

Predicted to enable serine-type endopeptidase activity. Involved in fertilization and sperm capacitation. Acts upstream of or within acrosome reaction and binding activity of sperm to zona pellucida. Located in acrosomal membrane. Is expressed in early conceptus; epididymis; gonad; and neural retina. Orthologous to human PCSK4 (proprotein convertase subtilisin/kexin type 4). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • proprotein convertase subtilisin/kexin type 4
  • KEX2-like endoprotease 3
  • neuroendocrine convertase 3
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Properties