Protein Name dipeptidyl peptidase 3
Organism Homo sapiens
Gene ID 10072
Gene Symbol

DPP3

UniProt Q9NY33 (DPP3_HUMAN), Q5JPB8 (Q5JPB8_HUMAN)
Relationships Total Number of functionally related compound(s) : 114
Total Number of Articles : 60
Description

dipeptidyl peptidase 3

Gene Summary

This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2012]

synonyms
  • dipeptidyl peptidase 3
  • DPP III
  • dipeptidyl aminopeptidase III
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Properties