Protein Name amyloid P component, serum
Organism Homo sapiens
Gene ID 325
Gene Symbol

APCS

UniProt P02743 (SAMP_HUMAN), V9HWP0 (V9HWP0_HUMAN)
Relationships Total Number of functionally related compound(s) : 247
Total Number of Articles : 247
Description

amyloid P component, serum

Gene Summary

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]

synonyms
  • serum amyloid P-component
  • 9.5S alpha-1-glycoprotein
  • epididymis secretory sperm binding protein Li 92n
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Properties