Protein Name serpin family F member 2
Organism Homo sapiens
Gene ID 5345
Gene Symbol

SERPINF2

UniProt P08697 (A2AP_HUMAN)
Relationships Total Number of functionally related compound(s) : 407
Total Number of Articles : 379
Description

serpin family F member 2

Gene Summary

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

synonyms
  • alpha-2-antiplasmin
  • alpha-2-AP
  • alpha-2-plasmin inhibitor
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Properties