Protein Name DEAD-box helicase 17
Organism Homo sapiens
Gene ID 10521
Gene Symbol

DDX17

UniProt Q92841 (DDX17_HUMAN), A0A5H1ZRQ2 (A0A5H1ZRQ2_HUMAN), Q59F66 (Q59F66_HUMAN)
Relationships Total Number of functionally related compound(s) : 65
Total Number of Articles : 59
Description

DEAD-box helicase 17

Gene Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011]

synonyms
  • probable ATP-dependent RNA helicase DDX17
  • DEAD (Asp-Glu-Ala-Asp) box helicase 17
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
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Properties