Protein Name aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Organism Homo sapiens
Gene ID 60496
Gene Symbol

AASDHPPT

UniProt Q9NRN7 (ADPPT_HUMAN)
Relationships Total Number of functionally related compound(s) : 63
Total Number of Articles : 47
Description

aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Gene Summary

The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]

synonyms
  • L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
  • 4'-phosphopantetheinyl transferase
  • LYS5 ortholog
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Properties