Protein Name apolipoprotein C3
Organism Rattus norvegicus
Gene ID 24207
Gene Symbol

Apoc3

UniProt A0A0G2K8Q1 (A0A0G2K8Q1_RAT)
Relationships Total Number of functionally related compound(s) : 26
Total Number of Articles : 26
Description

apolipoprotein C3

Gene Summary

Predicted to enable high-density lipoprotein particle receptor binding activity; lipase inhibitor activity; and phospholipid binding activity. Involved in several processes, including lipoprotein transport; negative regulation of oxidative phosphorylation; and positive regulation of triglyceride biosynthetic process. Located in extracellular space. Used to study hyperthyroidism; hypothyroidism; and type 1 diabetes mellitus. Biomarker of cholestasis. Human ortholog(s) of this gene implicated in several diseases, including apolipoprotein C-III deficiency; chronic kidney disease; coronary artery disease; familial hyperlipidemia (multiple); and glucose metabolism disease (multiple). Orthologous to human APOC3 (apolipoprotein C3). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • apolipoprotein C-III
  • apolipoprotein C-3
  • ApoC-III
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Properties