Protein Name nucleophosmin 1
Organism Rattus norvegicus
Gene ID 25498
Gene Symbol

Npm1

UniProt P13084 (NPM_RAT)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 7
Description

nucleophosmin 1

Gene Summary

Enables several functions, including anion binding activity; p53 binding activity; and protein kinase B binding activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of DNA metabolic process; and rRNA metabolic process. Located in nuclear matrix and nucleoplasm. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NPM1 (nucleophosmin 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • nucleophosmin
  • NPM
  • nucleolar phosphoprotein B23
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Properties