Protein Name kallikrein 1
Organism Rattus norvegicus
Gene ID 24523
Gene Symbol

Klk1

UniProt P36373 (KLK7_RAT)
Relationships Total Number of functionally related compound(s) : 26
Total Number of Articles : 20
Description

kallikrein 1

Gene Summary

Enables endopeptidase activity. Involved in several processes, including positive regulation of acute inflammatory response; positive regulation of apoptotic process; and response to nutrient. Located in acrosomal vesicle and apical part of cell. Biomarker of hypertension and pancreatitis. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • kallikrein 1
  • Kallikrein 1, renal/pancreas/salivary
  • esterase B
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Properties