| Protein Name | Mitogen-activated protein kinase kinase kinase nsy-1;mitogen-activated protein kinase kinase kinase |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 24104671 |
| Gene Symbol | nsy-1 |
| UniProt | A0A0K3ATZ5 (A0A0K3ATZ5_CAEEL) |
| Relationships |
Total Number of functionally related compound(s) :
5
Total Number of Articles : 3 |
Description |
Mitogen-activated protein kinase kinase kinase nsy-1;mitogen-activated protein kinase kinase kinase |
| Gene Summary |
Enables several functions, including MAP kinase kinase kinase activity; mitogen-activated protein kinase kinase binding activity; and transcription regulator activator activity. Involved in several processes, including defense response to other organism; oviposition; and p38MAPK cascade. Located in axon cytoplasm; neuronal cell body; and postsynaptic density. Is expressed in several structures, including AWC; hypodermis; intestine; rectal gland cell; and tail. Used to study amphetamine abuse. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to several human genes including MAP3K15 (mitogen-activated protein kinase kinase kinase 15) and MAP3K5 (mitogen-activated protein kinase kinase kinase 5). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |