Protein Name TATA-box binding protein associated factor 8
Organism Homo sapiens
Gene ID 129685
Gene Symbol

TAF8

UniProt Q7Z7C8 (TAF8_HUMAN)
Relationships Total Number of functionally related compound(s) : 128
Total Number of Articles : 124
Description

TATA-box binding protein associated factor 8

Gene Summary

This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

synonyms
  • transcription initiation factor TFIID subunit 8
  • TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
  • TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa
Click to show/hide the synonyms
Properties