Protein Name hydroxysteroid (17-beta) dehydrogenase 7
Organism Mus musculus
Gene ID 15490
Gene Symbol

Hsd17b7

UniProt O88736 (DHB7_MOUSE)
Relationships Total Number of functionally related compound(s) : 16
Total Number of Articles : 17
Description

hydroxysteroid (17-beta) dehydrogenase 7

Gene Summary

Enables 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity; 5-alpha-androstane-3-beta,17-beta-diol dehydrogenase (NADP+) activity; and estradiol 17-beta-dehydrogenase [NAD(P)+] activity. Involved in brain development; embryonic organ development; and steroid metabolic process. Acts upstream of or within several processes, including cholesterol biosynthetic process; embryonic skeletal system development; and nervous system development. Located in endoplasmic reticulum membrane. Is expressed in several structures, including autopod; extraembryonic component; eye; nervous system; and reproductive system. Orthologous to human HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7
  • 17-beta-HSD 7
  • 17-beta-hydroxysteroid dehydrogenase 7
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Properties