Protein Name T-box brain transcription factor 1
Organism Mus musculus
Gene ID 21375
Gene Symbol

Tbr1

UniProt Q64336 (TBR1_MOUSE)
Relationships Total Number of functionally related compound(s) : 12
Total Number of Articles : 10
Description

T-box brain transcription factor 1

Gene Summary

Enables DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including brain development; conditioned taste aversion; and specification of animal organ identity. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human TBR1 (T-box brain transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • T-box brain protein 1
  • T-box brain gene 1
  • T-brain-1
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Properties