Protein Name mitogen-activated protein kinase kinase kinase 11
Organism Rattus norvegicus
Gene ID 309168
Gene Symbol

Map3k11

UniProt Q66HA1 (M3K11_RAT)
Relationships Total Number of functionally related compound(s) : 31
Total Number of Articles : 32
Description

mitogen-activated protein kinase kinase kinase 11

Gene Summary

Enables ATP binding activity; JUN kinase kinase kinase activity; and enzyme binding activity. Involved in several processes, including JNK cascade; positive regulation of JNK cascade; and positive regulation of neuron apoptotic process. Predicted to be located in microtubule. Predicted to be active in centrosome. Orthologous to human MAP3K11 (mitogen-activated protein kinase kinase kinase 11). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • mitogen-activated protein kinase kinase kinase 11
  • mixed lineage kinase 3
  • Mlk-3
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Properties