Protein Name melanocortin 2 receptor
Organism Homo sapiens
Gene ID 4158
Gene Symbol

MC2R

UniProt Q01718 (ACTHR_HUMAN)
Relationships Total Number of functionally related compound(s) : 67
Total Number of Articles : 91
Description

melanocortin 2 receptor

Gene Summary

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014]

synonyms
  • adrenocorticotropic hormone receptor
  • ACTH receptor
  • MC2 receptor
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Properties