Protein Name sperm antigen with calponin homology and coiled-coil domains 1
Organism Homo sapiens
Gene ID 92521
Gene Symbol

SPECC1

UniProt Q5M775 (CYTSB_HUMAN), A0A024QYY9 (A0A024QYY9_HUMAN), B4E2A4 (B4E2A4_HUMAN), B4DW07 (B4DW07_HUMAN)
Relationships Total Number of functionally related compound(s) : 119
Total Number of Articles : 86
Description

sperm antigen with calponin homology and coiled-coil domains 1

Gene Summary

The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

synonyms
  • cytospin-B
  • cytokinesis and spindle organization B
  • nuclear structure protein 5
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Properties