Protein Name FYN proto-oncogene, Src family tyrosine kinase
Organism Rattus norvegicus
Gene ID 25150
Gene Symbol

Fyn

UniProt Q62844 (FYN_RAT), A0A096MKC1 (A0A096MKC1_RAT)
Relationships Total Number of functionally related compound(s) : 100
Total Number of Articles : 105
Description

FYN proto-oncogene, Src family tyrosine kinase

Gene Summary

Enables several functions, including phosphatidylinositol 3-kinase binding activity; protein tyrosine kinase activity; and signaling receptor binding activity. Involved in several processes, including cellular response to organonitrogen compound; negative regulation of cell death; and protein phosphorylation. Located in several cellular components, including mitochondrion; perinuclear endoplasmic reticulum; and postsynaptic density. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Alzheimer's disease and schizophrenia. Orthologous to human FYN (FYN proto-oncogene, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • tyrosine-protein kinase Fyn
  • FYN oncogene related to SRC, FGR, YES
  • p59-Fyn
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Properties