Protein Name adrenoceptor beta 2
Organism Rattus norvegicus
Gene ID 24176
Gene Symbol

Adrb2

UniProt Q8VBU7 (Q8VBU7_RAT)
Relationships Total Number of functionally related compound(s) : 258
Total Number of Articles : 510
Description

adrenoceptor beta 2

Gene Summary

Enables several functions, including G-protein alpha-subunit binding activity; beta2-adrenergic receptor activity; and signaling receptor binding activity. Involved in several processes, including chemical synaptic transmission; positive regulation of ion transport; and response to steroid hormone. Located in several cellular components, including caveola; neuronal cell body membrane; and sarcolemma. Is active in glutamatergic synapse. Used to study cardiomyopathy (multiple); congestive heart failure; kidney disease (multiple); and lung disease (multiple). Biomarker of several diseases, including acute kidney failure; artery disease (multiple); congestive heart failure; polycystic ovary syndrome; and ulcerative colitis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); disease of metabolism (multiple); kidney failure (multiple); lung disease (multiple); and open-angle glaucoma (multiple). Orthologous to human ADRB2 (adrenoceptor beta 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • beta-2 adrenergic receptor
  • Adrenergic beta 2- receptor surface
  • adrenergic receptor, beta 2
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Properties