Protein Name proopiomelanocortin
Organism Rattus norvegicus
Gene ID 24664
Gene Symbol


UniProt Q8K422 (Q8K422_RAT)
Relationships Total Number of functionally related compound(s) : 530
Total Number of Articles : 806


Gene Summary

Predicted to enable hormone activity and melanocortin receptor binding activity. Predicted to be involved in several processes, including cortisol secretion; positive regulation of cAMP-mediated signaling; and regulation of gene expression. Predicted to act upstream of or within several processes, including calcium-mediated signaling; glucose homeostasis; and regulation of glycogen metabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in familial Mediterranean fever; obesity; and osteoarthritis. Orthologous to human POMC (proopiomelanocortin). [provided by Alliance of Genome Resources, Apr 2022]

  • pro-opiomelanocortin
  • alpha-melanocyte-stimulating hormone
  • corticotropin-lipotropin
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