Protein Name C-C motif chemokine ligand 7
Organism Homo sapiens
Gene ID 6354
Gene Symbol

CCL7

UniProt P80098 (CCL7_HUMAN)
Relationships Total Number of functionally related compound(s) : 150
Total Number of Articles : 130
Description

C-C motif chemokine ligand 7

Gene Summary

This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]

synonyms
  • C-C motif chemokine 7
  • chemokine (C-C motif) ligand 7
  • monocyte chemoattractant protein 3
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Properties