Protein Name prostaglandin I receptor (IP)
Organism Mus musculus
Gene ID 19222
Gene Symbol

Ptgir

UniProt P43252 (PI2R_MOUSE), Q8CC99 (Q8CC99_MOUSE)
Relationships Total Number of functionally related compound(s) : 103
Total Number of Articles : 139
Description

prostaglandin I receptor (IP)

Gene Summary

Predicted to enable prostacyclin receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of platelet-derived growth factor receptor signaling pathway; and negative regulation of smooth muscle cell proliferation. Acts upstream of or within response to lipopolysaccharide. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; gallbladder; genitourinary system; hemolymphoid system gland; and limb segment. Orthologous to human PTGIR (prostaglandin I2 receptor). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • prostacyclin receptor
  • PGI receptor
  • PGI2 receptor
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Properties